Clinical significance of peri-operative change of serum inorganic phosphate levels after moderate-to-major abdominal surgery

Q4 Nursing

中华临床营养杂志 Pub Date : 2019-12-30 DOI:10.3760/CMA.J.ISSN.1674-635X.2019.06.002

Zhida Chen, Yunhe Gao, H. Xi, Tang Yun

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Abstract

Objective To analyze the occurrence and clinical significance of hypophosphatemia after moderate-to-major abdominal surgery. Methods A total of 120 patients who had received moderate to major abdominal surgery and then transferred to the intensive care unit (ICU) from January 2008 to October 2018 were retrospectively analyzed. The peri-operative parameters of serum inorganic phosphate and calcium levels were recorded and analyzed. The incidence of hypophosphatemia after the operation was calculated. The effect of phosphorus-supplement infusion on the complications and mortality within 30 days after the operation were observed. Results After moderate-to-major surgery, the phosphorus concentration significantly decreased [(1.21±0.27) vs. (0.83±0.24)mmol/L, P<0.05]; the incidence of hypophosphatemia was 58.3%, especially in patients with nutritional risk assessed before the operation. The post-operative complications were less in the phosphorus-supplement infusion group than in the control group (17.5% vs. 41.3%, P=0.028). Conclusion The incidence of hypophosphatemia is relatively high after moderate-to-major abdominal surgery, especially in patients with nutritional risks. The treatment of phosphorus-supplement infusion can benefit the patients in their short-term prognosis. Key words: Hypophosphatemia; Critically ill; Nutritional risk

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中大型腹部手术后围手术期血清无机磷水平变化的临床意义

目的分析中大型腹部手术后低磷血症的发生情况及临床意义。方法回顾性分析2008年1月至2018年10月共120例接受中至大腹部手术后转入重症监护室（ICU）的患者。记录和分析围手术期血清无机磷和钙水平的参数。计算术后低磷血症的发生率。观察补磷输液对术后30天内并发症及死亡率的影响。结果中、大手术后磷浓度明显下降[（1.21±0.27）vs.（0.83±0.24）mmol/L，P<0.05]；低磷血症的发生率为58.3%，尤其是在术前评估有营养风险的患者中。补磷组的术后并发症比对照组少（17.5%对41.3%，P=0.028）。结论中大型腹部手术后低磷血症的发生率相对较高，尤其是有营养风险的患者。补磷输液治疗可使患者的短期预后受益。关键词：低磷酸盐血症；病危；营养风险

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来源期刊

中华临床营养杂志 Nursing-Nutrition and Dietetics

CiteScore

0.20

自引率

0.00%

发文量

2282

期刊介绍： The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch. The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.