Diamond in medical devices and sensors: An overview of diamond surfaces

Nour Mani, Aaqil Rifai, Shadi Houshyar, Marsilea A. Booth, Kate Fox
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引用次数: 9

Abstract

Significant challenges arise when the human body is damaged, diseased and unable to repair itself. Current biomaterials for biomedical devices have limitations to restore function, while materials for implants and sensors often invoke a large foreign body response. Therefore, there is a need to develop suitable biomaterials in the fields of medical devices and sensors. Diamond is emerging due to its many favourable properties including biocompatibility, antimicrobial capability, antifouling properties, electrical conductivity and chemical functionalization capability. Thin film coatings of diamond can be fabricated by chemical vapour deposition, or by particle coatings with nanodiamond materials. Hybrid/composite diamond materials include soft materials such as those processed by electrospinning and melt extrusion, as well as hard materials such as those processed by additive manufacturing. Additive manufacturing is a developing area for diamond biomaterial fabrication and can include both hard and soft materials. The fabrication method used will depend on the properties required of the biomaterial, as well as the application. In this mini-review, recent progress on using diamond in medical devices and sensors is outlined, with particular emphasis on fabrication methods. We highlight selected applications from recent literature and, in closing, make comments and suggestions to advance the field and direction of diamond application in medical devices and sensors.

Abstract Image

医疗设备和传感器中的金刚石:金刚石表面概述
当人体受损、患病且无法自我修复时,就会出现重大挑战。目前用于生物医学设备的生物材料在恢复功能方面有局限性,而用于植入物和传感器的材料通常会引起很大的异物反应。因此,有必要在医疗设备和传感器领域开发合适的生物材料。金刚石因其具有生物相容性、抗菌性、防污性、导电性和化学功能化能力等诸多优良性能而日益受到重视。金刚石薄膜涂层可以通过化学气相沉积或纳米金刚石材料的颗粒涂层来制备。混合/复合金刚石材料包括软材料,如通过静电纺丝和熔融挤出加工的材料,以及硬材料,如通过增材制造加工的材料。增材制造是金刚石生物材料制造的一个发展领域,可以包括硬材料和软材料。所使用的制造方法将取决于所需要的生物材料的性质,以及应用。在这篇小型综述中,概述了在医疗设备和传感器中使用金刚石的最新进展,特别强调了制造方法。我们重点介绍了最近文献中选定的应用,并在结束时提出评论和建议,以推进金刚石在医疗设备和传感器中的应用领域和方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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