Comparison of IMRT plans with and without bone marrow sparing for the treatment of cervical cancer

Q3 Health Professions

Iranian Journal of Medical Physics Pub Date : 2020-12-15 DOI:10.22038/IJMP.2020.51442.1841

Sri Krishna Gangarapu, Srinivas Vuppu

引用次数: 0

Abstract

Background: The aim of the present study was to compare intensity-modulated radiation therapy (IMRT) plan with Bone Marrow sparing (BM-IMRT) and plan without Bone Marrow Sparing (N-IMRT). Materials and Methods: Fifteen cases of cervical cancer cases were selected for retrospective analysis. All the cases were previously treated with normal IMRT. For this study, plans with BM-IMRT were created again for all patients following Radiation Therapy Oncology Group (RTOG) guidelines. The prescribed dose (PD) of 50Gy in 25 fractions was given. The plan having coverage of 95% of PTV receiving 95% of prescribed dose was accepted. The plans were compared on the basis of planning target volume (PTV) coverage (dose to 2%, 98% of target), Constraints of OAR (Organs at Risk) were volume of 40% < 40Gy for normal bladder and rectum, (volume receiving dose 5Gy) V5

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骨髓保留和不保留治疗宫颈癌的IMRT方案的比较

背景:本研究的目的是比较有骨髓保留(BM-IMRT)和无骨髓保留(N-IMRT)的调强放疗(IMRT)计划。材料与方法:选取15例宫颈癌病例进行回顾性分析。所有病例先前均接受正常IMRT治疗。在这项研究中，根据放射治疗肿瘤组(RTOG)的指导方针，对所有患者再次制定了BM-IMRT计划。给药剂量(PD)为50Gy，分25份给药。接受了95%的PTV覆盖率和95%的处方剂量的计划。以计划靶体积(PTV)覆盖率(剂量为2%，靶的98%)为基础进行比较，OAR(危险器官)的限制为正常膀胱和直肠体积< 40Gy的40%(体积接受剂量为5Gy) V5

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Medical Physics Health Professions-Radiological and Ultrasound Technology

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Iranian Journal of Medical Physics (IJMP) is the official scientific bimonthly publication of the Iranian Association of Medical Physicists. IJMP is an international and multidisciplinary journal, peer review, free of charge publication and open access. This journal devoted to publish Original Papers, Review Articles, Short Communications, Technical Notes, Editorial and Letters to the Editor in the field of “Medical Physics” involving both basic and clinical research. Submissions of manuscript from all countries are welcome and will be reviewed by at least two expert reviewers.