The Influence of Propellant on the Technological Qualities of a Floating Aerosol

IF 0.4 Q4 PHARMACOLOGY & PHARMACY
Davtian Lena
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引用次数: 0

Abstract

Introduction: The aim of the research was to substantiate the amount of propellant in the composition of the aerosol concentrate, depending on the consumption characteristics of the film formed on the wound surface. The publication experimentally substantiates the concentration of propellant chladon-134a, which is a necessary component for the formation of a film-forming aerosol. Materials and Methods: The authors used modern research methods: Pharmacotechnological and physicochemical – to substantiate the optimal amount of propellant in the composition of the developed aerosol film forming. Results: Studies have shown that the type and amount of propellant affects the film formation. The authors found that depending on the amount of propellant in the balloon, the type of delivery of the solution from the balloon will change – or sprayed, or removed smoothly; the appearance of the film depends on the amount of propellant – smooth, shiny, as well as the percentage of concentrate dispensing from the aerosol container. Discussion and Conclusion: Physicochemical studies have proved the influence of propellant on the technological parameters of the film-forming aerosol: Type of delivery, appearance – colorless film with a smooth shiny surface; film thickness – 10–200 μ; drying time – 10–15 min; and the percentage yield of the contents of the aerosol container – 97.84 ± 2.31%. The use of propellant chladon 134a at a concentration of 10% was found to be optimal. At this concentration, the highest percentage yield of the contents of the aerosol container is ensured, which allows to obtain a film with a smooth type of delivery and satisfactory consumer characteristics.
推进剂对悬浮气溶胶工艺质量的影响
引言:研究的目的是根据伤口表面形成的薄膜的消耗特性,证实气溶胶浓缩物成分中推进剂的含量。该出版物通过实验证实了推进剂青瓷-134a的浓度,这是形成成膜气溶胶的必要成分。材料和方法:作者使用现代研究方法:药物技术和物理化学-来证实所开发的气溶胶成膜组成中的最佳推进剂量。结果:研究表明,推进剂的种类和用量对成膜有影响。作者发现,根据气球中推进剂的数量,从气球中输送溶液的类型会发生变化——或者被喷洒,或者被顺利移除;薄膜的外观取决于推进剂的数量——光滑、有光泽,以及从气溶胶容器中分配的浓缩物的百分比。讨论与结论:理化研究证明了推进剂对成膜气溶胶工艺参数的影响:发射类型、外观——无色薄膜,表面光滑有光泽;薄膜厚度–10–200μ;干燥时间–10–15分钟;气溶胶容器内容物的产率为97.84±2.31%。发现使用浓度为10%的推进剂青瓷134a是最佳的。在该浓度下,确保了气雾剂容器内容物的最高百分比产率,这允许获得具有平滑输送类型和令人满意的消费者特性的膜。
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来源期刊
Asian Journal of  Pharmaceutics
Asian Journal of Pharmaceutics PHARMACOLOGY & PHARMACY-
自引率
0.00%
发文量
47
期刊介绍: Character of the publications: -Pharmaceutics and Pharmaceutical Technology -Formulation Design and Development -Drug Discovery and Development Interface -Manufacturing Science and Engineering -Pharmacokinetics, Pharmacodynamics, and Drug Metabolism -Clinical Pharmacology, General Medicine and Translational Research -Physical Pharmacy and Biopharmaceutics -Novel Drug delivery system -Biotechnology & Microbiological evaluations -Regulatory Sciences
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