Chemical composition and antimicrobial activity of leave extract of Ocimum lamiifolium (Damakese) as a treatment for urinary tract infection

Cogent Chemistry Pub Date : 2018-01-01 DOI:10.1080/23312009.2018.1440894

Niguse Aweke Sahalie, Lijalem Hadush Abrha, L. D. Tolesa

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引用次数: 12

Abstract

Abstract Natural products obtained from aromatic plants are considered to be one of the potential sources for the screening of antimicrobial, antioxidant, and free radical scavenging agents. Ocimum Lamiifolium (Damakese) is one of the well-known celebrated and most widely used home remedies. The shade dried leaves of Ocimum Lamiifolium were subjected to hydrodistillation in a Clevenger-type apparatus to extract its essential oil. The yield of hydrodistilled colorless, pungent odor oil was found to be 0.22% (v/w). The chemical composition of the oil was analyzed by GC-MS method. Ten constituents were identified representing 93.56% of the total oil. The main constituents of the oil were found to be Linalool (28.52%) and 1-octen-3-yl-npropionate (20.82%) followed by 3,7,11-trimethyl-(E,E)-2,6,10-dodecatrienal (12.14%). The yield of crude extract of Ocimum Lamiifolium was 0.28% (w/w). Phytochemical screening revealed the presence of terpenoids, flavonoids, tannin, saponins and steroids. The in vitro antibacterial activity of Ocimum Lamiifolium leaf ethanol extract and essential oil was studied by using disc diffusion method. The oil exhibited significant zone of inhibitions against to E. coli bacterial strains.

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拉米夫林叶提取物治疗尿路感染的化学成分及抗菌活性

摘要从芳香植物中获得的天然产物被认为是筛选抗菌、抗氧化和自由基清除剂的潜在来源之一。大麦草（Damakese）是一种著名且使用最广泛的家庭疗法。在Clevenger型装置中对遮荫干燥的小叶进行水蒸馏以提取其精油。发现加氢蒸馏的无色、刺鼻气味的油的产率为0.22%（v/w）。采用气相色谱-质谱联用技术对其化学成分进行了分析。鉴定出10种成分，占总油量的93.56%。该油的主要成分为芳樟醇（28.52%）和1-辛烯-3-基丙酸酯（20.82%），其次为3,7,11-三甲基-（E，E）-2,6,10-十二碳三烯醛（12.14%）。植物化学筛选显示存在萜类、黄酮类、单宁、皂苷和类固醇。采用圆盘扩散法研究了苦艾叶乙醇提取物和精油的体外抗菌活性。该油对大肠杆菌菌株表现出显著的抑制区。

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Cogent Chemistry CHEMISTRY, MULTIDISCIPLINARY-

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