Deep Learning in Biomedical Data Science

IF 7 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
P. Baldi
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引用次数: 77

Abstract

Since the 1980s, deep learning and biomedical data have been coevolving and feeding each other. The breadth, complexity, and rapidly expanding size of biomedical data have stimulated the development of novel deep learning methods, and application of these methods to biomedical data have led to scientific discoveries and practical solutions. This overview provides technical and historical pointers to the field, and surveys current applications of deep learning to biomedical data organized around five subareas, roughly of increasing spatial scale: chemoinformatics, proteomics, genomics and transcriptomics, biomedical imaging, and health care. The black box problem of deep learning methods is also briefly discussed.
生物医学数据科学中的深度学习
自20世纪80年代以来,深度学习和生物医学数据一直在共同发展,相互促进。生物医学数据的广度、复杂性和迅速扩大的规模刺激了新型深度学习方法的发展,将这些方法应用于生物医学数据导致了科学发现和实际解决方案。本综述提供了该领域的技术和历史指针,并调查了当前深度学习在生物医学数据中的应用,这些数据组织在五个子领域,大致是越来越大的空间尺度:化学信息学、蛋白质组学、基因组学和转录组学、生物医学成像和医疗保健。本文还简要讨论了深度学习方法中的黑箱问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
11.10
自引率
1.70%
发文量
0
期刊介绍: The Annual Review of Biomedical Data Science provides comprehensive expert reviews in biomedical data science, focusing on advanced methods to store, retrieve, analyze, and organize biomedical data and knowledge. The scope of the journal encompasses informatics, computational, artificial intelligence (AI), and statistical approaches to biomedical data, including the sub-fields of bioinformatics, computational biology, biomedical informatics, clinical and clinical research informatics, biostatistics, and imaging informatics. The mission of the journal is to identify both emerging and established areas of biomedical data science, and the leaders in these fields.
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