Design of 4D printed shape-changing tracheal stent and remote controlling actuation

IF 4.5 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

International Journal of Smart and Nano Materials Pub Date : 2021-10-02 DOI:10.1080/19475411.2021.1974972

Fenghua Zhang, Nan Wen, Linlin Wang, Yunqi Bai, J. Leng

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引用次数: 35

Abstract

ABSTRACT As a kind of medical treatment device, shape memory tracheal stent has a good application prospect. The biodegradable stent can effectively reduce the damage to patients and improve the therapeutic performance of stents. In this work, a series of shape memory polylactic acid (Fe3O4) composite tracheal stents were manufactured by 4D printing. The composite tracheal stents with different structures were designed. Moreover, with the addition of magnetic particles Fe3O4, the shape memory PLA/Fe3O4 composite tracheal stent has a magnetic driving effect. Under the magnetic field, the shape recovery process is completed within 40 s, and the shape recovery rate is more than 99%. Moreover, the 4D printed tracheal stent was also triggered by the irradiation of infrared lamp to realize the remote controlling recovery. The research on the structure design and driving method of 4D printing tracheal stent expands the application scope of shape memory polymer composites in biomedical field, provides a new way for personalized implantable medical devices and minimally invasive surgery. It is of great significance for better precision medical treatment. Graphical abstract

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4D打印可变形气管支架的设计及遥控驱动

形状记忆气管支架作为一种医疗器械，具有良好的应用前景。生物可降解支架可以有效减少对患者的损伤，提高支架的治疗性能。本工作采用4D打印技术制备了一系列形状记忆聚乳酸（Fe3O4）复合气管支架。设计了不同结构的复合气管支架。此外，通过添加磁性颗粒Fe3O4，形状记忆PLA/Fe3O4复合气管支架具有磁性驱动作用。在磁场作用下，形状恢复过程在40秒内完成，形状恢复率超过99%。此外，4D打印的气管支架还通过红外线灯的照射触发，实现远程控制恢复。4D打印气管支架结构设计和驱动方法的研究拓展了形状记忆聚合物复合材料在生物医学领域的应用范围，为个性化植入式医疗器械和微创手术提供了新途径。这对于更好的精准医疗具有重要意义。图形摘要

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来源期刊

International Journal of Smart and Nano Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

6.30

自引率

5.10%

发文量

审稿时长

11 weeks

期刊介绍： The central aim of International Journal of Smart and Nano Materials is to publish original results, critical reviews, technical discussion, and book reviews related to this compelling research field: smart and nano materials, and their applications. The papers published in this journal will provide cutting edge information and instructive research guidance, encouraging more scientists to make their contribution to this dynamic research field.