Seroprevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State

Abstract

Context: Hepatitis B virus (HBV) infection is a cause of chronic liver disease, causing cirrhosis and hepatocellular carcinoma, and pregnant women are not spared. Perinatal transmission is a significant way that the disease is spread from mother to children who will eventually become adults and chronic carriers. This study sought to determine the burden of the disease among pregnant women. Aims: To estimate the prevalence and investigate possible factors associated with HBV infection among pregnant women attending antenatal clinics in DASH, Lafia. Settings and Design: A hospital-based descriptive cross-sectional survey conducted at the Obstetrics and Gynecology Department of DASH, Lafia, Nasarawa Methods and Material: Around 200 pregnant women who attended the ANC clinic were consecutively enrolled, their venous blood samples collected, and hepatitis B profile was carried out using commercially available rapid chromatographic kits Statistical Analysis Used: Data were collected by trained data collectors using a proforma, then entered into a predesigned program in the Epi-info version 3.5.4 (CDC, Atlanta, Georgia, USA) and analyzed. Results: The seroprevalence of HBV infection was high (8%) and there were no statistically significant associations between the infection and the investigated sociodemographic and other risk factors. Conclusions: The study showed that HBV is hyperendemic in this region, and antenatal screening for this virus is desirable to avert its sequelae in both mothers and their newborn babies.