The Canadian Cohort Obstructive Lung Disease (CanCOLD): New Insights for Primary Care Application

J. Bourbeau, W. Tan, H. Perrault
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Abstract

The Canadian Cohort Obstructive Lung disease (CanCOLD) study was launched ten years ago, to provide insight on the natural course of chronic obstructive pulmonary disease (COPD). This project, unique on the world scene for its longitudinal evaluation, is based on random sampling of the population as opposed to more traditional cohorts built on convenience samples of clinical patients. This comprehensive review article has elected to extract and collate from the set of CanCOLD substudies those findings and emerging discoveries that can serve to influence clinical practice, in particular, for primary care. We are presenting findings grouped around three aspects: prevalence of COPD, diagnostic performance, and impacts of COPD. Furthermore, the main results of these studies are supplemented by key messages. From CanCOLD publications we have already learned much, with sufficient substantive data to warrant translation into our clinical practice, guidelines and health policies for the benefit of our COPD patients. (BRN Rev. 2019;5(4):249-62) Corresponding author: Jean Bourbeau, jean.bourbeau@mcgill.ca
加拿大队列阻塞性肺疾病(CanCOLD):初级保健应用的新见解
加拿大队列阻塞性肺疾病(CanCOLD)研究于十年前启动,旨在深入了解慢性阻塞性肺疾病(COPD)的自然病程。该项目的纵向评估在世界范围内是独一无二的,它基于人口的随机抽样,而不是更传统的基于临床患者方便样本的队列。这篇综合综述文章选择从canold的子研究中提取和整理那些可能影响临床实践,特别是初级保健的发现和新发现。我们的研究结果围绕三个方面进行分组:COPD的患病率、诊断表现和COPD的影响。此外,这些研究的主要结果得到了关键信息的补充。从canold的出版物中,我们已经了解到很多,有足够的实质性数据可以保证将其转化为我们的临床实践、指南和健康政策,以造福我们的COPD患者。通讯作者:Jean Bourbeau, jean.bourbeau@mcgill.ca。(生物医学工程学报,2019;5(4):249-62
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