From Hyperthermia to Immunomodulating Polysaccharides

Abstract

Natural polysaccharides remain overlooked as part of naturally occurring bioactive molecules. The current knowledge results in numerous clinical trials, from first observations of their effects on various diseases to precise chemical characterization and decades of biological evaluation. The aim of this report is to summarize historical perspective of the route from the first anecdotical observation to the current position, with emphasis on some crucial turning points.