Evaluation of the Relationship between Salivary Resistin and pH in Healthy Individuals

Abstract

Changes in composition and flow rate of saliva depict secondary systematic variations related to diseases, drugs and treatment of illnesses. This research examines the relationship between the saliva pH and saliva resistin in the seemingly healthy individuals. In this study 82 patients referring to the Department of Oral Medicine, Faculty of Tabriz Dentistry were examined. Before sampling from the patients with inclusive conditions, their mouths were washed by water and after 15 minutes 5ml of their saliva were collected by drooling in the sterile polyethylene containers. The collected samples were transferred to the laboratory and their pH was measured. Then the enzyme-linked immunosorbent assay (ELISA) test was performed by specific kit for saliva resistin measuring. The mean value of saliva resistin was 15.60±7.56 and pH mean value was 7.61±0.68. Results showed that about 61% of patients had resistin higher than15 ng/ml. According to the analysis results, 15.9% of patients had pH less than 7 while 57.3% had pH between 7-8 and 26.8% had pH higher than 8. There was a positive relationship between saliva resistin and pH. Since salivary resistin levels vary in response to different clinical conditions, direct relationship between the saliva resistin and pH indicates that pH changes can depict risk factor for specific diseases.