Giant Basal Cell Carcinoma – a Case Report

I. Kapetanovic, V. Reljić, Martina Bosic, S. Popadic
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引用次数: 0

Abstract

Abstract Basal cell carcinoma is the most common form of cutaneous cancer. In majority of cases it is locally invasive with slow growth, ranging in size from a couple of milimeters to a couple of centimeters and located primarily on sun-exposed regions. Giant basal cell carcinoma, defined as a tumor that is larger than 5 cm in diameter, is a very rare type of cutaneous malignancy accounting for 0.5-1% of all basal cell carcinomas. We present a case of a 74-year-old man with a 17 x 14 cm giant basal cell carcinoma in the right supraclavicular region. Detailed history revealed that the lesion had started as a papule 15 years before presentation. Despite its growth, the lesion was neglected until admission. Histological examination of skin lesion confirmed superficial and focally infiltrative types of basal cell carcinoma. Electron radiotherapy was administered with 54 Gy total dose delivered in 20 daily fractions which resulted in healing of lesions and adequate response. Thus, definitive radiotherapy can be just as effective as excision when the criteria are met.
基底细胞巨癌一例报告
摘要基底细胞癌是癌症最常见的皮肤癌。在大多数情况下,它是局部侵袭性的,生长缓慢,大小从几毫米到几厘米不等,主要位于阳光照射的区域。巨大基底细胞癌是指直径大于5厘米的肿瘤,是一种非常罕见的皮肤恶性肿瘤,占所有基底细胞癌的0.5-1%。我们报告一例74岁男性右锁骨上区17 x 14厘米的巨大基底细胞癌。详细的病史显示,病变在出现前15年就开始是丘疹。尽管病变在生长,但在入院前一直被忽视。皮肤损伤的组织学检查证实了浅表和局灶浸润型基底细胞癌。电子放射治疗的总剂量为54Gy,分20天给药,使病变愈合并有足够的反应。因此,当符合标准时,明确的放射治疗可以和切除一样有效。
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期刊介绍: Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.
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