Outcome analysis of dorsal buccal mucosal graft urethroplasty in perimenopausal women with urethral stricture disease

IF 0.8 Q4 UROLOGY & NEPHROLOGY
A. Iyyan, P. Murugan, Shree Rajagopal, S. Sali
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引用次数: 0

Abstract

Purpose: To assess the clinical outcomes following dorsal buccal mucosal graft urethroplasty (BMGU) in perimenopausal women (PMW) suffering from urethral stricture disease. Materials and Methods: PMW (40–65 years) presenting with urinary symptoms were evaluated with uroflowmetry, voiding cystourethrogram (VCUG), and urethral calibration. PMW with maximum flow rate (Qmax) less than 10 ml/s or postvoid residual (PVR) volume greater than 50 ml, VCUG showing evidence of urethral stricture, and failure to calibrate with 14 Fr Foley catheter were included in the study. Patients with underactive bladder, carcinoma cervix, pelvic trauma, and oral submucosal fibrosis were excluded from the study. Patients satisfying inclusion and exclusion criteria underwent dorsal BMGU. Outcomes of the surgery were assessed by uroflowmetry at 3-monthly intervals. Results: The number of patients satisfying the inclusion and exclusion criteria between March 2014 and March 2020 was eight. The mean age of the patients was 52.1 years. The mean stricture length was 1.9 cm. The mean preoperative Qmax and PVR were 4.2 ml/s and 110 ml, respectively. The mean postoperative Qmax and PVR at 6 months were 15.4 ml/s and 39.1 ml, respectively. One patient had a recurrent stricture and underwent dilatation. Donor site complications were minor. The overall success rate of the procedure was 87%. Conclusion: Dorsal BMGU in females for urethral stricture disease offers successful urethral reconstruction and the advantage of least disruption of continence mechanism and resilience to hormonal changes in PMW.
围绝经期女性尿道狭窄疾病患者颊背黏膜移植尿道成形术的疗效分析
目的:评价口腔黏膜背侧移植物尿道成形术(BMGU)治疗围绝经期妇女尿道狭窄的临床效果。材料和方法:采用尿流量测定法、排尿膀胱尿道图(VCUG)和尿道校准法对有泌尿系症状的PMW(40-65岁)进行评估。PMW的最大流速(Qmax)小于10ml/s或排尿后残余量(PVR)大于50ml,VCUG显示尿道狭窄,以及未能使用14Fr Foley导管进行校准。膀胱功能不全、宫颈癌、骨盆创伤和口腔黏膜下纤维化的患者被排除在研究之外。符合纳入和排除标准的患者接受了背侧BMGU。每隔3个月通过尿流量测定法评估手术结果。结果:2014年3月至2020年3月期间,符合纳入和排除标准的患者人数为8人。患者的平均年龄为52.1岁。平均狭窄长度为1.9cm,术前平均Qmax和PVR分别为4.2ml/s和110ml。术后6个月的平均Qmax和PVR分别为15.4 ml/s和39.1 ml。一名患者出现复发性狭窄并接受了扩张术。供区并发症轻微。手术的总成功率为87%。结论:女性尿道狭窄患者的背侧BMGU可成功重建尿道,其优点是对控制机制的破坏最小,对PMW激素变化的恢复力强。
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来源期刊
Urological Science
Urological Science UROLOGY & NEPHROLOGY-
CiteScore
1.20
自引率
0.00%
发文量
26
审稿时长
6 weeks
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