Research on synthesis and property of nano-textured Sc2O3-MgO efficient antibacterial agents

IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
Ying Wang, Yanjing Liu, Xiyue Li, Yuezhou Liu, Fuming Wang, Yaping Huang, Bing Du, Yongfang Qian, Lihua Lv
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引用次数: 1

Abstract

In order to obtain the inorganic efficient antibacterial agents, the means of ion doping and morphology construction in this research are used to enhance the antibacterial property of nano-MgO, which is according to the “oxidative damage mechanism” and “contact mechanism”. In this work, the nano-textured Sc2O3-MgO are synthesized by doping Sc3+ in nano-MgO lattice through calcining at 600 °C. When the Sc3+ content reaches 10%, the nanotextures on the powders surface are pretty clearly visible and uniform, and the specific surface area and the oxygen vacancy are ideal, so that the 10% Sc3+-doped powders (SM-10) has the excellent antibacterial property against E. coli and S. aureus (MBC = 0.03 mg/mL). The efficient antibacterial agents in this research have a better antibacterial effect than the 0% Sc3+-doped powders (SM-0, MBC = 0.20 mg/mL) and the commercial nano-MgO (CM, MBC = 0.40 mg/mL), which have application prospects in the field of antibacterial.

Abstract Image

纳米结构Sc2O3-MgO高效抗菌剂的合成及性能研究
为了获得无机高效抗菌剂,本研究根据“氧化损伤机制”和“接触机制”,采用离子掺杂和形态构建等手段增强纳米mgo的抗菌性能。在600℃煅烧条件下,在纳米mgo晶格中掺杂Sc3+,合成了纳米结构Sc2O3-MgO。当Sc3+含量达到10%时,粉末表面的纳米结构清晰均匀,比表面积和氧空位理想,因此10% Sc3+掺杂粉末(SM-10)对大肠杆菌和金黄色葡萄球菌(MBC = 0.03 mg/mL)具有优异的抗菌性能。本研究的高效抗菌剂抗菌效果优于0% Sc3+掺杂粉末(SM-0, MBC = 0.20 mg/mL)和商用纳米mgo (CM, MBC = 0.40 mg/mL),在抗菌领域具有应用前景。
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来源期刊
JBIC Journal of Biological Inorganic Chemistry
JBIC Journal of Biological Inorganic Chemistry 化学-生化与分子生物学
CiteScore
5.90
自引率
3.30%
发文量
49
审稿时长
3 months
期刊介绍: Biological inorganic chemistry is a growing field of science that embraces the principles of biology and inorganic chemistry and impacts other fields ranging from medicine to the environment. JBIC (Journal of Biological Inorganic Chemistry) seeks to promote this field internationally. The Journal is primarily concerned with advances in understanding the role of metal ions within a biological matrix—be it a protein, DNA/RNA, or a cell, as well as appropriate model studies. Manuscripts describing high-quality original research on the above topics in English are invited for submission to this Journal. The Journal publishes original articles, minireviews, and commentaries on debated issues.
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