Estimation of Some Immunoglobulins Classes and Innate Immunity Parameters in BOM Cases

Abstract

Immune response against OM infections depends mainly on Humoral mediated Immunity (HMI). From this scientific fact, the present study took care with the estimation of some immunological parameters related to these infections immunological response. Total W.B.C.s count was estimated. Furthermore Radial Immune Diffusion (RID) method was used in determination of Immunoglubulins IgG, IgM and IgA; also complement components C3 and C4 levels were estimated using Endoplate kits too. Results: OM Infections resultant from gram positive cocci increased total W.B.Cs counts, IgG, IgM, IgA, C3 and C4 complement components levels; in non-immunologicaly compromised patients comparing with the values of the peoples of control groups for all the parameters that estimated. Conclusions: Otitis media is a common infection in both children and adults. Gram positive suppurative OM caused; significant elevations in Total W.B.C.s counts, Immunoglubulins IgG, IgM and IgA and the complement components C3 and C4. Since HMI is the immunological response against these infections.