Cerebral Hemodynamics Influence on the Current and Prediction of Hepatic Encephalopathy

Abstract

Among patients of different ages with hepatocirrhosis of A, B, C virus viral etiology in Child-Pugh, chronic hepatic encephalopathy of all stages may occur along with discirculatory disorders with the development of chronic cerebrovascular insufficiency. The Reitan test duration is more than 200 seconds, blood flow hemispheric asymmetry is more than 40%, the decrease in the velocity parameters of the blood flow and the indices of vascular resistance in the basins of the middle cerebral arteries decrease below the reference values are associated with the adverse hepatic encephalopathy prognosis. The degrees of cognitive and discirculatory disorders are interrelated with the compensation stages for hepatocirrhosis. An increase of cognitive impairment degree from the logical thinking ability and attention to time and space disorientation is registered along with discirculatory disorders and cirrhosis compensation stage decrease.