{"title":"Abdominal skin metastasis in endometrial cancer","authors":"Eccita Rahestyningtyas, Pungky Mulawardhana, Tomy Lesmana","doi":"10.20473/MOG.V27I22019.84-89","DOIUrl":null,"url":null,"abstract":"Objectives: Surgical wound metastases in stage 1 endometrial cancer are possible, with a variety of different pathophysiological possibilities. Comprehensive management is needed to keep the patient on the possibility of a good prognosis.Cases Report: During January 2015 – January 2018 at dr. Soetomo Hospital, there were 2 cases of metastatic endometrial cancer in the laparotomy wounds by which the condition is very rare. Case 1, The patient was diagnosed with endometrial carcinoma following the results of curettage. Anatomical pathology examination was done and obtained grade 2 endometrioid adenocarcinoma. In Case 2, the patient underwent Total Abdominal Hysterectomy and Bilateral Salpingo-Oophorectomy in 2013 at Mojokerto General Hospital, indicating Uterine Fibroids and Ovarian Cysts. The results of anatomical pathology examination were unknown. On April 2017, the patient complained abdominal swelling since 3 months ago.Conclusion: In January 2015 - January 2018, 2 cases of metastatic endometrial cancer was found in a former laparotomy operation where this condition is very rare in endometrial cancer cases with low grade ,so that follow-up, monitoring and more vigilance are required in patients with low-grade endometrial Ca who have finished undergoing a surgery and chemotherapy. Rapture or mass resection, followed by external radiation, may be performed in patients with recurrence in the laparotomy wound area or in patients with high risk factors for endometrial cancer such as a history of estrogen use, tamoxifen, nullipara, obesity, diabetes mellitus, and family history of endometrial cancer. Currently, there is no fixed procedure (guideline) in RS. Dr. Soetomo to overcome recurrences especially in the scars of cancer surgery.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Majalah Obstetri dan Ginekologi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20473/MOG.V27I22019.84-89","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Objectives: Surgical wound metastases in stage 1 endometrial cancer are possible, with a variety of different pathophysiological possibilities. Comprehensive management is needed to keep the patient on the possibility of a good prognosis.Cases Report: During January 2015 – January 2018 at dr. Soetomo Hospital, there were 2 cases of metastatic endometrial cancer in the laparotomy wounds by which the condition is very rare. Case 1, The patient was diagnosed with endometrial carcinoma following the results of curettage. Anatomical pathology examination was done and obtained grade 2 endometrioid adenocarcinoma. In Case 2, the patient underwent Total Abdominal Hysterectomy and Bilateral Salpingo-Oophorectomy in 2013 at Mojokerto General Hospital, indicating Uterine Fibroids and Ovarian Cysts. The results of anatomical pathology examination were unknown. On April 2017, the patient complained abdominal swelling since 3 months ago.Conclusion: In January 2015 - January 2018, 2 cases of metastatic endometrial cancer was found in a former laparotomy operation where this condition is very rare in endometrial cancer cases with low grade ,so that follow-up, monitoring and more vigilance are required in patients with low-grade endometrial Ca who have finished undergoing a surgery and chemotherapy. Rapture or mass resection, followed by external radiation, may be performed in patients with recurrence in the laparotomy wound area or in patients with high risk factors for endometrial cancer such as a history of estrogen use, tamoxifen, nullipara, obesity, diabetes mellitus, and family history of endometrial cancer. Currently, there is no fixed procedure (guideline) in RS. Dr. Soetomo to overcome recurrences especially in the scars of cancer surgery.
目的:手术伤口转移在1期子宫内膜癌中是可能的,具有多种不同的病理生理可能性。需要综合管理,以保持患者良好预后的可能性。病例报告:2015年1月至2018年1月,在dr. Soetomo医院,有2例转移性子宫内膜癌在剖腹手术伤口,这种情况非常罕见。病例1:患者经刮宫检查诊断为子宫内膜癌。解剖病理检查为2级子宫内膜样腺癌。病例2于2013年在Mojokerto总医院行全腹子宫切除术和双侧输卵管卵巢切除术,诊断为子宫肌瘤和卵巢囊肿。解剖病理检查结果未知。患者于2017年4月主诉腹部肿胀3个月。结论:2015年1月- 2018年1月,既往剖腹手术中发现2例转移性子宫内膜癌,这种情况在低级别子宫内膜癌病例中非常罕见,因此对完成手术和化疗的低级别子宫内膜癌患者需要随访、监测和提高警惕。剖腹手术创面复发的患者,或有雌激素、他莫昔芬、子宫内膜癌、肥胖、糖尿病、子宫内膜癌家族史等子宫内膜癌高危因素的患者,均可行剖腹手术或肿块切除后行外放射线治疗。目前,RS. Dr. Soetomo没有固定的程序(指南)来克服复发,特别是在癌症手术的疤痕。