Axitinib-induced posterior reversible encephalopathy syndrome in a patient with renal cell carcinoma

Abstract

A 51-year-old male patient presented with a generalized tonic-clonic type seizure. He had a history of renal cell carcinoma and had received axitinib 2 weeks before this seizure event due to the unresponsiveness to the previous chemotherapeutics. He did not experience any neurologic symptoms previously. His vital rhythm showed elevated blood pressure and tachycardia. He became deeply drowsy soon after the seizure attack, with no definite later-alizing or localizing signs.