Well Controlled Blood Pressure in Turkish Patients: How Many Drugs Are Required to Attain and Maintain the Blood Pressure Goal?

M. Temizel, Ugur Dilek Calap, M. Cit, Mansur Azermir, Y. Arman
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Abstract

Background: This study aimed to determine the number of antihypertensive agents required to achieve optimal blood pressure (BP) in Turkish hypertensive patients. Material and Methods: Totally 400 hypertensive patients (114 males and 286 females) were enrolled. BP was measured by patients at home twice a day. The patients were called for controlling in every four weeks, and those who had BP 140/90 drug, doses were increased or another antihypertensive drug added and the patients were continued to be followed-up. Results: In the first follow-up (on the 4th week), 152 (38%) patients, including 35 (31%) men and 117 (41%) women, attained the goal BP. The mean duration of hypertension in single, double, triple, and quadruple treatment groups was 6.2 ± 5.0, 6.8 ± 5.9, 8.8 ± 5.4, and 10.4 ± 6.6 years, respectively. In the beginning, the median number of agents used for each patient was 2.17. When the follow-up was concluded, the median of agents used for each patient was 2.72. Conclusion: Thirty-eight percent of participants had controlled hypertension in the first follow-up. Women had better BP control. The median number of agents required for attaining and maintaining BP goal was 2.72. More drugs are needed when hypertension gets longer.
土耳其患者血压控制良好:需要多少药物才能达到和维持血压目标?
背景:本研究旨在确定土耳其高血压患者达到最佳血压(BP)所需的降压药数量。材料与方法:共纳入400例高血压患者(男114例,女286例)。患者在家中测量血压,每天两次。每4周进行一次对照,对血压140/90的患者,增加剂量或加用另一种降压药,继续随访。结果:第1次随访(第4周),152例(38%)患者达到目标血压,其中男性35例(31%),女性117例(41%)。单、双、三和四组患者的平均高血压病程分别为6.2±5.0年、6.8±5.9年、8.8±5.4年和10.4±6.6年。开始时,每位患者使用的药物中位数为2.17种。随访结束时,每位患者使用的药物中位数为2.72。结论:38%的参与者在第一次随访中高血压得到控制。女性有更好的血压控制。达到和维持BP目标所需药物的中位数为2.72。当高血压病程延长时,需要更多的药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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