Is Nasal Nitric Oxide Measurement an Useful Diagnostic Tool in Respiratory Diseases?

Acta Medica Martiniana Pub Date : 2023-04-01 DOI:10.2478/acm-2023-0002

Lucanska Miroslava, Kunc Peter, Pecova Renata

引用次数: 0

Abstract

Abstract Nasal nitric oxide (nNO), discovered in exhaled air in 1991, is produced in the nose and paranasal sinuses. This small gaseous molecule plays various roles in the organism, e.g. the first line defense through its antiviral and antimicrobial activity, stimulation of ciliary motility, regulation of pulmonary function. The measurement of nNO has become a diagnostic tool in various diagnoses, such as primary ciliary dyskinesia, allergic rhinitis, chronic rhinosinusitis, and others. In this article, we discuss the potential benefit of nNO measurement in diagnosis and monitoring of various respiratory diseases.

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鼻腔一氧化氮检测是呼吸系统疾病的有效诊断工具吗?

鼻一氧化氮(nNO)于1991年在呼出的空气中被发现，它是在鼻子和鼻窦中产生的。这种小的气体分子在生物体中发挥着多种作用，例如，通过其抗病毒和抗菌活性作为第一道防线，刺激纤毛运动，调节肺功能。nNO的测量已成为各种诊断的诊断工具，如原发性纤毛运动障碍、变应性鼻炎、慢性鼻窦炎等。在本文中，我们讨论了nNO测量在诊断和监测各种呼吸系统疾病中的潜在益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Medica Martiniana

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： Acta Medica Martiniana is a medical scientific journal, first published in print form in December 2001. It is a continuation of the journal / almanac Folia Medica Martiniana (1971 - 1996). The journal‘s owner is the Jessenius Faculty of Medicine, Comenius University, Slovakia. Dissemination of research results and scientific knowledge from all areas of medicine and nursing. Stimulation, facilitation and supporting of publication activity for the young medical research and clinical generation. The contributions of young novice authors (PhD students and post-doctorials) are particularly welcome. Acta Medica Martiniana is an open-access journal, with a periodicity of publishing three times per year (Apr/Aug/Dec). It covers a wide range of basic medical disciplines, such as anatomy, histology, biochemistry, human physiology, pharmacology, etc., as well as all clinical areas incl. preventive medicine, public health and nursing. Interdisciplinary and multidisciplinary manuscripts, including papers from all areas of biomedical research, are welcome.