Anti-CASPR2 and Epilepsy: don’t forget to think about it

Abstract

Autoimmune encephalitis (AE) is an important cause of seizures. With the discovery of highly specific neuronal-antibodies the recognition of the clinical syndrome associated with each marker is crucial to the right diagnosis and treatment regime. In this short review we summarize the importance of CASPR2 antibodies in unknown etiology seizures and its epileptogenesis.