Correlation between vitamin D levels and cognitive impairment on 90 days post ischemic stroke patients

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2022-09-30 DOI:10.37897/rjn.2022.3.7

Rizaldy Taslim Pinzon, Nindya Stephanie Christina, Oey Yedida Stephanie Sugianto, Tillandsia Filli Folia Primastuti

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引用次数: 0

Abstract

The prevalence of ischemic stroke based on the American Heart Association (AHA) data in 2019 reached 77.2 million people. As much as 72% of post ischemic stroke patients got cognitive impairment. Vitamin D deficiency is often found in post-stroke patients and causes functional decline. This study aims to assess the relationship between vitamin D levels and cognitive impairment in 90 days post ischemic stroke patients. This study is a cross-sectional study using secondary data from medical records at Bethesda Hospital Yogyakarta taken from January to March 2021. Cognitive impairment in 90 days post ischemic stroke patients were assessed using MMSE (Mini-Mental State Examination) and CDT (Clock Drawing Test). This study was analyzed through univariate tests and bivariate tests using Spearman correlation. This proves a correlation between vitamin D levels and cognitive impairment which is formulated by the value of MMSE (p=0.000) and CDT (p=0.031). The mean of vitamin D levels was 13.53±3.625. The proportion of hypovitaminosis D was divided into 5.7% of insufficiency patients and 94.3% patients stated as deficiency. The lower the vitamin D levels, the lower the MMSE and CDT values accordingly. In conclusion, there is a relationship between vitamin D levels and cognitive impairment in 90 days post ischemic stroke patients. Low levels of vitamin D result in more frequent and more severe cognitive impairments.

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缺血性脑卒中后90天维生素D水平与认知功能障碍的相关性

根据美国心脏协会（AHA）2019年的数据，缺血性中风的患病率达到7720万人。高达72%的缺血性脑卒中后患者出现认知障碍。维生素D缺乏症常见于脑卒中后患者，并导致功能下降。本研究旨在评估缺血性中风患者90天后维生素D水平与认知障碍之间的关系。这项研究是一项横断面研究，使用了2021年1月至3月日惹贝塞斯达医院医疗记录的二次数据。使用MMSE（迷你精神状态检查）和CDT（时钟描记测试）评估缺血性卒中后90天患者的认知障碍。本研究采用单变量检验和Spearman相关双变量检验进行分析。这证明了维生素D水平与认知障碍之间的相关性，该相关性由MMSE（p=0.000）和CDT（p=0.031）的值表示。维生素D水平的平均值为13.53±3.625。维生素D缺乏症的比例分为5.7%的维生素缺乏症患者和94.3%的维生素缺乏病患者。维生素D水平越低，MMSE和CDT值相应地就越低。总之，维生素D水平与缺血性卒中后90天患者的认知障碍之间存在关系。低水平的维生素D会导致更频繁、更严重的认知障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.