Difference in prevalence of diabetes and diabetic retinopathy among low-altitude dwellers vs. high-altitude dwellers in North India

Q4 Medicine

Asian Journal of Ophthalmology Pub Date : 2020-01-15 DOI:10.35119/ASJOO.V17I1.441

Anil Chauhan, A. Verma, D. Sharma, Lalit R. Gupta, Dinesh Kumar, G. Sharma, A. Grover

{"title":"Difference in prevalence of diabetes and diabetic retinopathy among low-altitude dwellers vs. high-altitude dwellers in North India","authors":"Anil Chauhan, A. Verma, D. Sharma, Lalit R. Gupta, Dinesh Kumar, G. Sharma, A. Grover","doi":"10.35119/ASJOO.V17I1.441","DOIUrl":null,"url":null,"abstract":"Background: Type-2 diabetes mellitus (DM) is one of the leading lifestyle-related chronic disease as its prevalence is expected to rise up to 24.0% in the world by 2025, which was only 6.3% in year 2003. \nObjective: To understand the high-altitude and low-altitude differentials for DM and diabetic retinopathy (DR) prevalence in a sub-Himalayan state of North India. \nMethods: The study was carried out in the Shahpur block of Kangra district (altitude 2,404 feet) and the Spiti block of Lahaul and Spiti district (altitude 12,500 feet) of Himachal Pradesh. \nResults: Among diabetics, the prevalence of DR was observed to be high (18.1%) in low landers and low (5.0%) in high landers. DM was more of a problem among low landers with a prevalence of 12.3% when compared to high landers (7.2%). Overall, the odd ratio of DR was twice as high (2.2; 95% confidence interval [CI]: 1.1-2.3) among patients with an unsatisfactory level of HbA1c (>8.0%) adjusted for gender, age group, smoking status and hypertension. \nConclusion: Differential did exist, as DM and DR were significantly lower in high-altitude areas when compared to low-altitude areas.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":"17 1","pages":"19-29"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35119/ASJOO.V17I1.441","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Type-2 diabetes mellitus (DM) is one of the leading lifestyle-related chronic disease as its prevalence is expected to rise up to 24.0% in the world by 2025, which was only 6.3% in year 2003. Objective: To understand the high-altitude and low-altitude differentials for DM and diabetic retinopathy (DR) prevalence in a sub-Himalayan state of North India. Methods: The study was carried out in the Shahpur block of Kangra district (altitude 2,404 feet) and the Spiti block of Lahaul and Spiti district (altitude 12,500 feet) of Himachal Pradesh. Results: Among diabetics, the prevalence of DR was observed to be high (18.1%) in low landers and low (5.0%) in high landers. DM was more of a problem among low landers with a prevalence of 12.3% when compared to high landers (7.2%). Overall, the odd ratio of DR was twice as high (2.2; 95% confidence interval [CI]: 1.1-2.3) among patients with an unsatisfactory level of HbA1c (>8.0%) adjusted for gender, age group, smoking status and hypertension. Conclusion: Differential did exist, as DM and DR were significantly lower in high-altitude areas when compared to low-altitude areas.

查看原文本刊更多论文

印度北部低海拔居民与高海拔居民糖尿病和糖尿病视网膜病变患病率的差异

背景:2型糖尿病(DM)是与生活方式相关的主要慢性疾病之一，预计到2025年全球患病率将从2003年的6.3%上升至24.0%。目的:了解印度北部亚喜马拉雅地区DM和糖尿病视网膜病变(DR)患病率的高海拔和低海拔差异。方法:研究在喜马偕尔邦康格拉地区的Shahpur区块(海拔2404英尺)和拉胡尔的斯皮提区块和斯皮提地区(海拔12500英尺)进行。结果:糖尿病患者中，低海拔人群DR患病率高(18.1%)，高海拔人群DR患病率低(5.0%)。低海拔地区的糖尿病患病率为12.3%，而高海拔地区的糖尿病患病率为7.2%。总的来说，DR的奇数比是两倍高(2.2;95%可信区间[CI]: 1.1-2.3)，在调整性别、年龄组、吸烟状况和高血压后，HbA1c水平不理想(bbb8.0%)的患者中。结论:差异确实存在，高海拔地区DM和DR明显低于低海拔地区。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Asian Journal of Ophthalmology Medicine-Ophthalmology

自引率

0.00%

发文量

期刊介绍： Asian Journal of OPHTHALMOLOGY is the official peer-reviewed journal of the South East Asia Glaucoma Interest Group (SEAGIG) and is indexed in EMBASE/Excerpta Medica. Asian Journal of OPHTHALMOLOGY is published quarterly (four [4] issues per year) by Scientific Communications International Limited. The journal is published on-line only and is distributed free of cost via the SEAGIG website.