Etiology of chronic liver disease in patients admitted at the National Referral Hospital of Bhutan in 2020.

Journal of community medicine and public health reports Pub Date : 2021-09-21 DOI:10.38207/jcmphr/2021/0208149

Tshering Penjor, Kuenzang Chhezom, Sithar Dorjee, G. P. Dhakal

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Abstract

Background and Aim: Chronic liver disease (CLD) is a major cause of morbidity and mortality worldwide. Etiologically there are many factors including hepatitis B virus (HBV) and C virus (HCV) infections, alcohol, non-alcoholic fatty liver disease, autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, Wilson’s disease, hemochromatosis, etc. Though there is evidence in the literature regarding the etiologies of CLD, no study was done in Bhutan in this area. Therefore, this study was conducted to assess the etiology of CLD in patients admitted in the National Referral Hospital, Thimphu. Methods: A descriptive study was conducted with 71 patients admitted to the National Referral Hospital. The study was done after seeking ethical clearance from the Research Ethics Board of Health (REBH) (Annexure 3) and was conducted from 1st January to 31st December 2020. The data were collected in pro forma and entered in Epi Data version 3.1 and analyzed using Epi Data Analysis version 2.2.2.183 and STATA version 15.1. Results: Out of 71 patients who had CLD, majority 80.3 % were due to alcohol and the least 2 (2.8 %) was due to the combination of alcohol and HBV infection. Conclusion: The study found that the commonest cause of CLD in patients admitted at the National Referral The hospital was alcohol. The findings from this study could help in strengthening the implementation of alcohol policy in the country.

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2020年不丹国家转诊医院收治患者的慢性肝病病因。

背景和目的：慢性肝病（CLD）是全球发病率和死亡率的主要原因。从病因上讲，有许多因素，包括乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）感染、酒精、非酒精性脂肪肝、自身免疫性肝炎、原发性胆汁性胆管炎、原发硬化性胆管管炎、Wilson病、血色素沉着病等。尽管文献中有关于CLD病因的证据，但在不丹没有进行这方面的研究。因此，本研究旨在评估廷布国家转诊医院收治的CLD患者的病因。方法：对国家转诊医院收治的71例患者进行描述性研究。该研究是在向卫生研究伦理委员会（REBH）寻求伦理许可后进行的（附录3），于2020年1月1日至12月31日进行。数据以形式收集并输入Epi data 3.1版，并使用Epi data Analysis 2.2.2.183版和STATA 15.1版进行分析。结果：在71例CLD患者中，大多数80.3%是由酒精引起的，至少2例（2.8%）是由酒精和HBV感染联合引起的。结论：研究发现，在国家转诊医院住院的患者中，CLD最常见的原因是酒精。这项研究的结果可能有助于加强该国酒精政策的实施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of community medicine and public health reports

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