Safeguarding human rights to health: a systematic review of supply chain impediments to safe medicines in developing nations

IF 1.2 Q4 HEALTH POLICY & SERVICES

International Journal of Human Rights in Healthcare Pub Date : 2023-08-31 DOI:10.1108/ijhrh-05-2023-0036

A. Loomba

{"title":"Safeguarding human rights to health: a systematic review of supply chain impediments to safe medicines in developing nations","authors":"A. Loomba","doi":"10.1108/ijhrh-05-2023-0036","DOIUrl":null,"url":null,"abstract":"\nPurpose\nA key feature of human rights in health is access to safe, effective and affordable medicines. Pharmacovigilance is advocated for monitoring intended/unintended effects of medicines to assure their safety. The purpose of this paper is to synthesize knowledge about supply chain impediments to safe medicines in developing nations and contribute to future development of research in this field.\n\n\nDesign/methodology/approach\nThis paper conducts a structured literature review based on Preferred Reporting Items for the Systematic Reviews and Meta-Analyses guidelines. It aims at profiling supply chain impediments to safe medicines in developing nations by reviewing 46 recent pharmacovigilance-specific papers published between 2005 and 2020.\n\n\nFindings\nAnalysis of reviewed articles identified criticality of supply chain impediments that affect constituents across pharmaceutical in developing nations, which still struggle to maintain robust national pharmacovigilance systems due to lack of awareness, policy and practices.\n\n\nResearch limitations/implications\nResearch results can be applied by pharmaceutical industry decision-makers and drug safety professionals in developing nations. Because the review is qualitative in nature, its implication ought to be tested after actual implementation.\n\n\nPractical implications\nThis review can help identify underinvestigated impediments and methods to aid in developing new pharmacovigilance knowledge areas in developing nation context.\n\n\nSocial implications\nThe review uncovers gaps in global health equity dialogue in developing nations. It also recognizes that macrolevel supply chain impediments exist due to unfair disease burden and health inequities in developing nations.\n\n\nOriginality/value\nThe paper examines supply chain impediments to safe medicines in developing nations with insights for future pharmacovigilance research. Identifying and classifying supply chain impediments through this review is the first step toward creating effective interventions for these impediments to safe medicines.\n","PeriodicalId":14129,"journal":{"name":"International Journal of Human Rights in Healthcare","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Human Rights in Healthcare","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1108/ijhrh-05-2023-0036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEALTH POLICY & SERVICES","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose A key feature of human rights in health is access to safe, effective and affordable medicines. Pharmacovigilance is advocated for monitoring intended/unintended effects of medicines to assure their safety. The purpose of this paper is to synthesize knowledge about supply chain impediments to safe medicines in developing nations and contribute to future development of research in this field. Design/methodology/approach This paper conducts a structured literature review based on Preferred Reporting Items for the Systematic Reviews and Meta-Analyses guidelines. It aims at profiling supply chain impediments to safe medicines in developing nations by reviewing 46 recent pharmacovigilance-specific papers published between 2005 and 2020. Findings Analysis of reviewed articles identified criticality of supply chain impediments that affect constituents across pharmaceutical in developing nations, which still struggle to maintain robust national pharmacovigilance systems due to lack of awareness, policy and practices. Research limitations/implications Research results can be applied by pharmaceutical industry decision-makers and drug safety professionals in developing nations. Because the review is qualitative in nature, its implication ought to be tested after actual implementation. Practical implications This review can help identify underinvestigated impediments and methods to aid in developing new pharmacovigilance knowledge areas in developing nation context. Social implications The review uncovers gaps in global health equity dialogue in developing nations. It also recognizes that macrolevel supply chain impediments exist due to unfair disease burden and health inequities in developing nations. Originality/value The paper examines supply chain impediments to safe medicines in developing nations with insights for future pharmacovigilance research. Identifying and classifying supply chain impediments through this review is the first step toward creating effective interventions for these impediments to safe medicines.

查看原文本刊更多论文

保障健康人权：对发展中国家安全药品供应链障碍的系统审查

目的健康人权的一个主要特点是获得安全、有效和负担得起的药物。药物警戒被提倡用于监测药物的预期/非预期效果，以确保其安全性。本文的目的是综合有关发展中国家安全药品供应链障碍的知识，并为该领域未来的研究发展做出贡献。设计/方法论/方法本文根据系统评价和荟萃分析指南的首选报告项目进行结构化文献综述。它旨在通过审查2005年至2020年间发表的46篇最近的药物警戒特定论文来分析发展中国家安全药物的供应链障碍。对审查文章的分析确定了影响发展中国家药物成分的供应链阻碍的关键性，由于缺乏意识、政策和实践，这些国家仍难以维持健全的国家药物警戒系统。研究局限性/含义发展中国家的制药行业决策者和药品安全专业人员可以应用研究结果。由于审查本质上是定性的，其含义应该在实际实施后进行测试。实际意义这篇综述有助于确定研究不足的障碍和方法，以帮助在发展中国家背景下开发新的药物警戒知识领域。社会影响该审查揭示了发展中国家在全球卫生公平对话方面的差距。它还认识到，由于发展中国家不公平的疾病负担和健康不平等，宏观层面的供应链存在障碍。原创性/价值该论文考察了发展中国家安全药物的供应链障碍，为未来的药物警戒研究提供了见解。通过这项审查识别和分类供应链障碍是为这些安全药物障碍制定有效干预措施的第一步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Human Rights in Healthcare HEALTH POLICY & SERVICES-

CiteScore

2.90

自引率

7.10%

发文量

期刊介绍： nternational Journal of Human Rights in Healthcare (IJHRH) is an international, peer reviewed journal with a unique practical approach to promoting race equality, inclusion and human rights in health and social care. The journal publishes scholarly and double blind peer-reviewed papers of the highest standard, including case studies and book reviews. IJHRH aims include: -To explore what is currently known about discrimination and disadvantage with a particular focus on health and social care -Push the barriers of the human rights discourse by identifying new avenues for healthcare practice and policy internationally -Create bridges between policymakers, practitioners and researchers -Identify and understand the social determinants of health equity and practical interventions to overcome barriers at national and international levels. The journal welcomes papers which use varied approaches, including discussion of theory, comparative studies, systematic evaluation of interventions, analysis of qualitative data and study of health and social care institutions and the political process. Papers published in IJHRH: -Clearly demonstrate the implications of the research -Provide evidence-rich information -Provoke reflection and support critical analysis of both challenges and strengths -Share examples of best practice and ‘what works’, including user perspectives IJHRH is a hugely valuable source of information for researchers, academics, students, practitioners, managers, policy-makers, commissioning bodies, social workers, psychologists, nurses, voluntary sector workers, service users and carers internationally.