SARS-COV-2 Infection, COVID-19 Disease, And Impact on Cardiology: A Review of Literature

Abstract

Coronavirus disease 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) has been declared a global pandemic. SARS-COV-2 greatly impacted the global population with its evolving variants. All over, COVID-19 caused a huge global health burden by systemic inflammation, multiorgan dysfunctions, and critical illness with a wide range of clinical manifestations. The cardiovascular (CV) system has been a focus of major morbidity and mortality with COVID-19 disease. Many potential mechanisms have been reported on CV impact by the SARS-COV-2 virus; medications used in the treatment of COVID-19 disease have various effects on the CV system; long-COVID associated morbidity is a growing topic to explore. As knowledge on COVID-19 evolves, this review aims to summarise relevant data on SARS-COV-2 virus infection and COVID-19 disease-related CV morbidity and mortality burden with a focus on potential mechanisms, and impact of long-COVID on the CV system