Hemolytic uremic syndrome following COVID-19; a case report

IF 0.2 Q4 UROLOGY & NEPHROLOGY

Journal of Renal Injury Prevention Pub Date : 2022-03-04 DOI:10.34172/jrip.2022.31972

Elham Emami, Samane Safari, Pedram Javanmard

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Abstract

High incidence of thromboembolic diseases in patients with coronavirus disease 2019 (COVID-19) have been reported that can affect several organs ranging from cutaneous thrombosis to pulmonary embolism, stroke, coronary thrombosis or kidney infarction. There are two proposed mechanisms for these phenomena, disseminated intravascular coagulation (DIC) and endotheliopathy. We report a case of 11-year-old girl presented to the emergency department with generalized tonic colonic seizure with upward gaze which was repeated in emergency room. Respiratory distress and loss of consciousness happened which led to her intubation. Due to increased serum creatinine levels and impaired consciousness which was associated with thrombocytopenia and hemolysis, she underwent plasmapheresis three times by the diagnosis of hemolytic uremic syndrome. Additionally, antihypertensive therapy was conducted. The patient’s condition improved and was discharged with good circumstances. Two weeks later the patient returned with thromboembolism that happened in the distal part of her left hand which underwent fasciotomy and thrombectomy.

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新冠肺炎后溶血性尿毒症综合征；病例报告

据报道，2019冠状病毒病（新冠肺炎）患者的血栓栓塞性疾病发病率很高，可影响多种器官，包括皮肤血栓形成、肺栓塞、中风、冠状动脉血栓形成或肾梗死。这些现象有两种机制，弥散性血管内凝血（DIC）和内皮病变。我们报告了一例11岁女孩因向上凝视的全身性强直性结肠痉挛在急诊室就诊的病例。呼吸窘迫和意识丧失导致她插管。由于血清肌酐水平升高和意识受损（与血小板减少和溶血有关），她接受了三次血浆置换术，诊断为溶血性尿毒症综合征。此外，还进行了抗高血压治疗。病人的病情有所好转，出院时情况良好。两周后，患者再次出现血栓栓塞，发生在左手远端，接受了筋膜切开术和血栓切除术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.