Left main coronary artery bifurcation coronary intervention in a patient with achondroplasia with multivessel coronary artery disease

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Indian Journal of Medical Specialities Pub Date : 2022-07-01 DOI:10.4103/injms.injms_144_21

Debasish Das, A. Banerjee, Abhinav Kumar, Tutan Das, S. Singh, J. Gupta, Manaranjan Dixit

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Abstract

We report a rare case of critical coronary artery disease in a 62-year-old male with achondroplasia. There is a paucity of case reports of association of achondroplasia with coronary artery disease. Left main coronary artery (LMCA) bifurcation lesion carries the highest risk of mortality out of all types of coronary artery lesions and patients with achondroplasia have two-fold more mortality as compared to the general population. That is why achondroplasia patients may be having more sudden cardiac death with the most catastrophic LMCA bifurcation lesion before they undergo revascularization. It may be the plausible explanation behind no literature description of LMCA bifurcation lesion in patients with achondroplasia. Our case is the first literature description of LMCA bifurcation lesion with successful intervention in achondroplasia. The present case will also provide a detailed insight into the association of achondroplasia with coronary artery disease without the presence of conventional cardiac risk factors.

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一例软骨发育不全伴多支冠状动脉疾病患者的左冠状动脉主干分叉冠状动脉介入治疗

我们报告了一例罕见的严重冠状动脉疾病，患者是一名患有软骨发育不全的62岁男性。软骨发育不全与冠状动脉疾病相关的病例报告很少。在所有类型的冠状动脉病变中，左主冠状动脉（LMCA）分叉病变的死亡率最高，软骨发育不全患者的死亡率是普通人群的两倍。这就是为什么软骨发育不全患者在进行血运重建之前，可能会出现更多的心脏性猝死，并伴有最严重的LMCA分叉病变。这可能是没有文献描述软骨发育不全患者LMCA分叉病变的合理解释。我们的病例是首次文献描述LMCA分叉病变并成功干预软骨发育不全。本病例还将在不存在传统心脏风险因素的情况下，详细了解软骨发育不全与冠状动脉疾病的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-

自引率

16.70%

发文量

期刊介绍： The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.