Minimal Change Disease in Young Adults: A Case Report

Abstract

Minimal Change Disease (MCD) represents the most common type of nephrotic syndrome in children (~80%), whereas in adults it accounts for 10% to 20% of cases. It seems to be associated with pollen allergy, asthma, NSAIDS use, and Hypoxia. A 25 years old girl with edema in both legs and facial puffiness and no other complain came to the clinic, her lab test was normal except for proteinuria 3.34g/24h and blood Albumin 1.9mg/dl, her ultrasonography for the kidneys was normal. Kidney Biopsy was normal and IF study was negative for immune related diseases. She was treated with corticosteroid; cyclosporine then tacrolimus so she could have good response.