Combined Heart and Kidney Transplantation: Initial Clinical Experience

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
F. Atik, Carolina de Castro Borges, M. Ulhoa, R. Chaves, Vitor Barzilai, R. Biondi, Tiago Martins de Almeida, Isabela Medeiros, H. Cardoso
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引用次数: 0

Abstract

Introduction Combined solid organ transplantation is infrequently performed in Brazil. The objective of this article is to present our initial experience with combined heart and kidney transplantation. Methods From January 2007 to December 2019, four patients were submitted to combined heart and kidney transplantation. Their mean age was 55.7±4.4 years, and three (75%) patients were males. All patients had Chagas cardiomyopathy, two were hospitalized and inotrope dependent, and all patients were on preoperative dialysis (median of 12 months prior to transplant). Results All patients survived and were in New York Heart Association functional class I at the latest follow-up (mean 34.7±17.5 months). Mean retarded kidney graft function was 22.9±9.7 days. One patient lost the kidney graft two years after the transplant due to Polyomavirus infection. Conclusion Our initial experience of combined heart and kidney transplantation was favorable in selected patients with advanced heart failure and end-stage kidney disease. It requires involvement of a dedicated multispecialty team throughout all the diagnostics and treatment steps.
心肾联合移植:初步临床经验
联合实体器官移植在巴西并不常见。本文的目的是介绍我们在心脏和肾脏联合移植方面的初步经验。方法2007年1月至2019年12月,4例患者行心肾联合移植。平均年龄55.7±4.4岁,男性3例(75%)。所有患者均患有恰加斯心肌病,其中2例住院并依赖于肌力,所有患者术前透析(移植前12个月中位数)。结果所有患者均存活,最新随访时纽约心脏协会功能分级为I级(平均34.7±17.5个月)。移植肾功能迟滞平均为22.9±9.7天。一名患者因多瘤病毒感染在移植两年后失去了肾移植。结论我们对晚期心力衰竭和终末期肾病患者进行心脏和肾脏联合移植的初步经验是有利的。它需要一个专门的多专业团队参与所有的诊断和治疗步骤。
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来源期刊
Revista Brasileira De Cirurgia Cardiovascular
Revista Brasileira De Cirurgia Cardiovascular CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.10
自引率
0.00%
发文量
176
审稿时长
20 weeks
期刊介绍: Brazilian Journal of Cardiovascular Surgery (BJCVS) is the official journal of the Brazilian Society of Cardiovascular Surgery (SBCCV). BJCVS is a bimonthly, peer-reviewed scientific journal, with regular circulation since 1986. BJCVS aims to record the scientific and innovation production in cardiovascular surgery and promote study, improvement and professional updating in the specialty. It has significant impact on cardiovascular surgery practice and related areas.
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