Current stem cells technologies used in medicine

Q4 Biochemistry, Genetics and Molecular Biology
Maria Müller, Julia Czarnecka, M. Brzeziński, Jakub Pruś, B. Kulak, Andrzej Hołubowski, M. Stasiak, B. Borowiec, Rut Bryl, Lisa Moncrieff, M. Dyszkiewicz-Konwińska
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引用次数: 3

Abstract

Abstract Stem cells and their usage for a long time are thought to be the future and hope in modern medicine. In this review we summarize development in science and bioengineering in this field. Opening with a description of newly discovered and studied sources of stem cells acquisition we present scientific methods progress and their application like 3D printing or transdifferentiation mode of action and results of these techniques. Technologies of genome editing like transcription activator-like effector nuclease, zinc-finger nucleases, or CRISPR Cas9 are also presented. In disease treatment and tissue reconstruction stem cells have proved to be effective most times due to great proliferation and differentiation potentials in presented in this summary pre-clinical and clinical studies for diseases like peripheral nerve palsy, myocardial infarction and heart ischemic disease and corneal wound healing. Running title: Current stem cells technologies used in medicine
目前干细胞技术在医学上的应用
摘要干细胞及其长期应用被认为是现代医学的未来和希望。在这篇综述中,我们总结了科学和生物工程在这一领域的发展。首先介绍了新发现和研究的干细胞获取来源,我们介绍了科学方法、进展及其应用,如3D打印或转分化作用模式以及这些技术的结果。还介绍了基因组编辑技术,如转录激活子样效应核酸酶、锌指核酸酶或CRISPR-Cas9。在疾病治疗和组织重建中,干细胞由于具有巨大的增殖和分化潜力,在大多数情况下都被证明是有效的。本综述介绍了干细胞对周围神经麻痹、心肌梗死和心脏缺血性疾病以及角膜伤口愈合等疾病的临床前和临床研究。运行标题:当前用于医学的干细胞技术
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来源期刊
Medical Journal of Cell Biology
Medical Journal of Cell Biology Biochemistry, Genetics and Molecular Biology-Cell Biology
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