Short-term therapeutic effect of flow diverter on small unruptured intracranial aneurysms

Q4 Medicine

中华神经外科杂志 Pub Date : 2019-11-28 DOI:10.3760/CMA.J.ISSN.1001-2346.2019.11.005

Li Li, Tianxiao Li, Qiuji Shao, Liang-fu Zhu, Jiang-yu Xue, Zi-liang Wang, W. Bai, Du Guangming

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Abstract

Objective To summarize the short-term therapeutic effect and safety of flow diverter (FD) in the treatment of small unruptured intracranial aneurysms. Methods From April 2014 to March 2019, clinical data were collected from 110 patients with 145 small (diameter < 10 mm) unruptured intracranial aneurysms who were admitted to Department of Neurosurgery, People′s Hospital of Zhengzhou University. Among those, 133 aneurysms were treated with FD alone and 12 aneurysms were treated with FD combined with coiling. Radiological outcomes were assessed based on the Raymond grading. Clinical outcomes were assessed based on the modified Rankin scale score (mRS). Results A total of 121 FD were used for 145 aneurysms. The successful rate of stent implantation was 99% (120/121). For 17 FD, balloon dilatation or massage were performed for better cell opening and wall apposition. There were no hemorrhagic complications. Ischemic complications occurred in 5 cases (4.5%). At 6 months post surgery, DSA results showed that Raymond grade Ⅰ embolism rate was 67.6% (50/74). Asymptomatic stenosis of parent artery was found in 2 cases. The 6-month follow-up results showed the mRS score of 0 in 101 cases, 1 in 4 cases, 2 in 3 cases, and 4 in 1 case and 5 in 1 case. Conclusions Treatment of small unruptured intracranial aneurysms with FD is associated with high success rate and safety. The 6-month follow-up results seem satisfactory and the long-term treatment results still need further follow-up. Key words: Intracranial aneurysm; Treatment outcome; Flow diverter; Unruptured; Small

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血流分流器治疗颅内未破裂小动脉瘤的近期疗效

目的总结血流分流术(FD)治疗颅内未破裂小动脉瘤的近期疗效及安全性。方法收集2014年4月至2019年3月郑州大学人民医院神经外科收治的110例颅内小动脉瘤(直径< 10 mm) 145例的临床资料。其中，单独应用FD治疗133个动脉瘤，FD联合卷绕治疗12个动脉瘤。放射学结果根据雷蒙德分级进行评估。临床结果以改良Rankin量表评分(mRS)评估。结果145个动脉瘤共使用了121个FD。支架置入率99%(120/121)。对于17 FD，行球囊扩张或按摩以获得更好的细胞开放和壁贴壁。无出血性并发症。发生缺血性并发症5例(4.5%)。术后6个月，DSA结果显示Raymond级Ⅰ栓塞率为67.6%(50/74)。2例无症状母动脉狭窄。随访6个月，mRS评分为0分101例，4例1分，3例2分，1例4分，1例5分。结论FD治疗颅内未破裂小动脉瘤成功率高，安全性好。6个月随访结果满意，远期治疗效果仍需进一步随访。关键词:颅内动脉瘤;治疗效果;流分流;未破裂;小

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来源期刊

中华神经外科杂志 Medicine-Surgery

CiteScore

0.10

自引率

0.00%

发文量

10706

期刊介绍： Chinese Journal of Neurosurgery is one of the series of journals organized by the Chinese Medical Association under the supervision of the China Association for Science and Technology. The journal is aimed at neurosurgeons and related researchers, and reports on the leading scientific research results and clinical experience in the field of neurosurgery, as well as the basic theoretical research closely related to neurosurgery.Chinese Journal of Neurosurgery has been included in many famous domestic search organizations, such as China Knowledge Resources Database, China Biomedical Journal Citation Database, Chinese Biomedical Journal Literature Database, China Science Citation Database, China Biomedical Literature Database, China Science and Technology Paper Citation Statistical Analysis Database, and China Science and Technology Journal Full Text Database, Wanfang Data Database of Medical Journals, etc.