Changes of the Types and Daily Costs of Topical Antiglaucoma Medications from 2006 to 2021 in China

IF 2.1 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Shuang Zhang, Xuefang Jia, Ying Gao, Lingling Wu
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Abstract

Purpose. To investigate the changes of the types and daily costs of topical antiglaucoma medications from 2006 to 2021 in China, providing evidence for optimizing treatment regimen and medical insurance policy. Methods. The types of topical antiglaucoma drugs except complementary and traditional medicines and associated price information were collected from the largest pharmaceutical database in China (YAOZH database). The daily costs of each drug, the average income level, and the daily cost of topical antiglaucoma medications relative with daily disposable income were calculated and compared between 2006 and 2021. Results. The options of topical antiglaucoma drugs increased remarkably to 32 types in 2021, of which prostaglandin analogs comprised the largest proportion (31.25%). There were 10 types of the same brand drugs available in 2006 and 2021, the mean daily cost of which decreased from $0.39 ± 0.30 to $0.28 ± 0.23 ( p < 0.001 ). As the average daily disposable income of Chinese residents grew greatly, the proportion of the daily cost of topical antiglaucoma medications in daily disposable income in 2021 declined significantly from 32.52% to 5.78% (all the drugs, p < 0.001 ) and 3.94% (without unit dose package, p < 0.001 ) in rural areas and from 9.95% to 2.31% (all the drugs, p < 0.001 ) and 1.57% (without unit dose package, p < 0.001 ) in urban areas. Conclusions. Topical antiglaucoma medications available become much more abundant in China. With the increase of residents’ disposable income and reduction of daily costs of topical antiglaucoma medications, the drug treatment for glaucoma becomes more affordable both in rural and urban areas.
2006 - 2021年中国局部抗青光眼药物种类及日常费用的变化
目的。了解2006 - 2021年中国抗青光眼外用药物种类及日常费用的变化情况,为优化治疗方案和医保政策提供依据。方法。除补充药和传统药外,外用抗青光眼药物的种类及相关价格信息收集自中国最大的药品数据库(YAOZH数据库)。计算并比较2006年至2021年各药物的日费用、平均收入水平、外用抗青光眼药物的日费用与日可支配收入的关系。结果。局部抗青光眼药物的选择在2021年显著增加至32种,其中前列腺素类似物所占比例最大(31.25%)。2006年和2021年共有10种同品牌药品可供选择,日均用药费用由0.39±0.30美元降至0.28±0.23美元(p < 0.001)。随着我国居民人均日可支配收入的大幅增长,2021年,外用抗青光眼药物的日费用占居民日可支配收入的比例,农村从32.52%下降到5.78%(全部药品,p < 0.001)和3.94%(无单位剂量包装,p < 0.001),城市从9.95%下降到2.31%(全部药品,p < 0.001)和1.57%(无单位剂量包装,p < 0.001)。结论。在中国,可用的局部抗青光眼药物越来越多。随着居民可支配收入的增加和日常局部抗青光眼药物费用的降低,青光眼的药物治疗在农村和城市都变得更加负担得起。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.10
自引率
5.00%
发文量
226
审稿时长
6 months
期刊介绍: The Journal of Clinical Pharmacy and Therapeutics provides a forum for clinicians, pharmacists and pharmacologists to explore and report on issues of common interest. Reports and commentaries on current issues in medical and pharmaceutical practice are encouraged. Papers on evidence-based clinical practice and multidisciplinary collaborative work are particularly welcome. Regular sections in the journal include: editorials, commentaries, reviews (including systematic overviews and meta-analyses), original research and reports, and book reviews. Its scope embraces all aspects of clinical drug development and therapeutics, including: Rational therapeutics Evidence-based practice Safety, cost-effectiveness and clinical efficacy of drugs Drug interactions Clinical impact of drug formulations Pharmacogenetics Personalised, stratified and translational medicine Clinical pharmacokinetics.
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