Surgical Management and Early Outcome of Encephalocele

P. Kafle, M. Sharma, S. Shilpakar, G. Sedain, Amit Pradhanang, A. Thapa, R. Shrestha, B. Rajbhandari, B. Khanal
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Abstract

Background: There are limited studies pertaining to management of encephalocele in Nepal. So the present study seems justifiable to bridge the gap in the literature on encephalocele from Nepal on its clinical profile and early outcome. This study aims to characterize the clinical profile, management and outcome of largest series of encephalocele at tertiary care center in Nepal. Materials and Methods: A retrospective analysis of encephalocele, managed surgically at two tertiary care centers between 2015 and 2020, was performed. Results: Total of 25 cases was surgically managed in the present study. The median age of study population was 2.5 months. There were 11 male and 14 female with male to female ratio of 1:1.26. Occipital encephalocele was the most common variant. Lump in the head (n=11) was the commonest clinical presentation followed by hyperteliorism (n=10). One patient presented with cleft lip and one had CSF discharge in a case of occipital encephalocele. Bony defect was the common radiological findings. Excision and repair was the most common mode of surgery leading to good outcome. Mortality rate was 4% with morbidity of 20%. Conclusion: Early surgical excision and tight dural closure with repair of bony defect is the standard treatment with relatively good outcome.
脑膨出的外科治疗与早期疗效
背景:关于尼泊尔脑膨出治疗的研究有限。因此,目前的研究似乎有理由弥合尼泊尔关于脑膨出的临床概况和早期结果的文献差距。本研究旨在描述尼泊尔三级保健中心最大系列脑膨出的临床概况、管理和结果。材料和方法:回顾性分析2015年至2020年在两家三级医疗中心手术治疗的脑膨出。结果:本组手术治疗25例。研究人群的中位年龄为2.5个月。男性11人,女性14人,男女比例为1:1.26。枕部脑膨出是最常见的变异。头部肿块(n=11)是最常见的临床表现,其次是远视(n=10)。一个病人提出了唇裂和一个有脑脊液放电的情况下,枕脑膨出。骨缺损是常见的影像学表现。切除和修复是最常见的手术模式,导致良好的结果。死亡率为4%,发病率为20%。结论:早期手术切除硬脑膜并硬脑膜紧密闭合修复骨缺损是标准的治疗方法,效果较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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16 weeks
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