Necrobiotic xanthogranuloma and monoclonal gammopathy

Q4 Medicine
V. Sandecká
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引用次数: 0

Abstract

paraproteinemia, multiple organ involvement, and an increased risk of developing lymphoproliferative malignancy, such as multiple myeloma, chronic lymphocytic leukemia, or Hodgkin and non-Hodgkin lymphoma. The present article describes a complicated case of a female patient diagnosed with multiple myeloma and necrobiotic xanthogranuloma whose serious health complications were not typical for the diagnosis of multiple myeloma. A thorough diagnostic algorithm and multidisciplinary cooperation of various experts led to the definitive diagnosis. The article also includes a description of the treatment strategy using combination therapy of daratumumab plus lenalidomide and dexamethasone with intravenous administration of immunoglobulins.
坏死性黄色肉芽肿与单克隆gammopathy
副蛋白血症,多器官受累,以及发生淋巴增生性恶性肿瘤的风险增加,如多发性骨髓瘤,慢性淋巴细胞白血病,或霍奇金淋巴瘤和非霍奇金淋巴瘤。本文报告一例复杂的多发性骨髓瘤合并坏死性黄色肉芽肿的女性患者,其严重的健康并发症在多发性骨髓瘤的诊断中并不典型。全面的诊断算法和各专家的多学科合作导致了明确的诊断。这篇文章还描述了使用达拉单抗、来那度胺和地塞米松联合治疗以及静脉注射免疫球蛋白的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Onkologie (Czech Republic)
Onkologie (Czech Republic) Medicine-Oncology
CiteScore
0.10
自引率
0.00%
发文量
43
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