Seroprevalence of SARS-Cov-2 Virus Infection In Kermanshah, Iran: A Population-based Cross-Sectional Study

Q3 Nursing

Open Public Health Journal Pub Date : 2023-03-08 DOI:10.2174/18749445-v16-e230308-2022-92

F. Shadmani, F. Najafi, Kamyar Mansori, M. Moradi, M. Rezaei, Nayebali Rezvani, M. Darbandi, M. Yoosefi, Zahra Laghei, A. Bozorgomid, Pegah Salahshoor, E. Shakiba

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Abstract

The aim of this study was to estimate the seroprevalence of SARS-CoV-2 infection in a general population from Kermanshah province, Iran. The present study was a population-based cross-sectional design conducted in Kermanshah province in 2020. Sampling was performed in a multi-stage process, and 1967 participants were considered, and also 174 interviewers were assigned to collect data online. Then, 5 mL of blood sample was taken from every participant. The blood samples were centrifuged with the ELISA method to detect SARS-CoV-2-specific IgG and IgM antibodies in serum samples. Seropositive prevalence was adjusted by means of survey analysis. Case fatality rate (CFR) and infection fatality rate (IFR) were estimated. A total of 1967 people from 14 cities of the province participated in the study. The mean age of participants was 35.7±16.9, and 50.4% were female. The lowest and highest seroprevalence was found in the cities of Paveh (2.3% [0.3- 4.2]) and Harsin (61.6% [54.7–68.5]), respectively. The CFR and IFR in men and women were 3.4 vs. 3.3 and 0.1 vs. 0.3. The aged 60 years or older had the highest CFR and IFR with 11.2 and 3.7%, respectively. The prevalence of SARS-CoV-2 infection and IFR among the general population of Kermanshah province was 18.3 and 0.3%, respectively. The results of this study can assist the policymaker in assessing risk factors, and transmission dynamics of SARS-CoV-2 in a population and implementing preventive and control interventions.

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伊朗Kermanshah地区SARS-Cov-2病毒感染的血清阳性率:一项基于人群的横断面研究

本研究的目的是估计伊朗克尔曼沙赫省普通人群中严重急性呼吸系统综合征冠状病毒2型感染的血清流行率。本研究是2020年在克尔曼沙省进行的基于人群的横断面设计。抽样是在一个多阶段的过程中进行的，共有1967名参与者被考虑在内，174名受访者被指派在线收集数据。然后，从每个参与者身上抽取5mL血样。用ELISA方法离心血样，检测血清样品中的严重急性呼吸系统综合征冠状病毒2型特异性IgG和IgM抗体。通过调查分析调整血清阳性率。估计病死率（CFR）和感染致死率（IFR）。共有来自全省14个城市的1967人参加了这项研究。参与者的平均年龄为35.7±16.9岁，50.4%为女性。血清流行率最低和最高的城市分别是帕维（2.3%[0.3-4.2]）和哈辛（61.6%[54.7-68.5]）。男性和女性的CFR和IFR分别为3.4比3.3和0.1比0.3。60岁及以上的CFR和IFR最高，分别为11.2%和3.7%。克尔曼沙省普通人群中严重急性呼吸系统综合征冠状病毒2型感染和IFR的患病率分别为18.3%和0.3%。这项研究的结果可以帮助决策者评估严重急性呼吸系统综合征冠状病毒2型在人群中的风险因素和传播动态，并实施预防和控制干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Public Health Journal Social Sciences-Health (social science)

CiteScore

1.00

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0.00%

发文量

期刊介绍： The Open Public Health Journal is an Open Access online journal which publishes original research articles, reviews/mini-reviews, short articles and guest edited single topic issues in the field of public health. Topics covered in this interdisciplinary journal include: public health policy and practice; theory and methods; occupational health and education; epidemiology; social medicine; health services research; ethics; environmental health; adolescent health; AIDS care; mental health care. The Open Public Health Journal, a peer reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.