Overview of hyaluronic acid and its development as dermal fillers gel

Abstract

Since the late 1990s, when the first commercially available hyaluronic acid-based tissue filler appeared, HA fillers have become the “product of choice” of soft tissue augmentation due to their favourable safety profile and minimally invasive nature of the treatment. Recent years have increased the popularity of HA fillers among doctors and patients and the number of available HA fillers and indications for aesthetic treatments. Due to the greater availability, and growing awareness among patients, HA filler treatments have become one of the most frequently performed cosmetic procedures worldwide. For several decades, we have been observing the development and progress of improving fillers to increase the safety and effectiveness of performed treatments.