Taha A. Baiomy , Ola A. Harb , Ahmed A. Obaya , Loay M. Gertallah
{"title":"Primary splenic non-Hodgkin lymphoma of diffuse large B cell type; a case report and review of the literature","authors":"Taha A. Baiomy , Ola A. Harb , Ahmed A. Obaya , Loay M. Gertallah","doi":"10.1016/j.ehpc.2020.200459","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Primary splenic lymphoma (PSL) is rare anatomical subtype of non-Hodgkin lymphoma which primarily originated from and limited to the spleen without other sites invasion, with a 6 months interval before lymphoma appearance in other locations.</p></div><div><h3>Case presentation</h3><p>In the present report we described a case of a female patient aged 59 years old with pathologically confirmed PSL.</p><p>The patient was with a left upper quadrant abdominal pain since 3 month. Radiological evaluation revealed diffuse splenomegaly. The patient underwent splenectomy and the histopathological examination of the spleen revealed high-grade non-Hodgkin B-cell lymphoma.</p></div><div><h3>Conclusions</h3><p>It is important to put in consideration that PSL although a rare, but must be considered as a differential diagnosis, in a patient with splenomegaly and abdominal pain in absence of specific clinical findings.</p></div>","PeriodicalId":38075,"journal":{"name":"Human Pathology: Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehpc.2020.200459","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Pathology: Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214330020301085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1
Abstract
Background
Primary splenic lymphoma (PSL) is rare anatomical subtype of non-Hodgkin lymphoma which primarily originated from and limited to the spleen without other sites invasion, with a 6 months interval before lymphoma appearance in other locations.
Case presentation
In the present report we described a case of a female patient aged 59 years old with pathologically confirmed PSL.
The patient was with a left upper quadrant abdominal pain since 3 month. Radiological evaluation revealed diffuse splenomegaly. The patient underwent splenectomy and the histopathological examination of the spleen revealed high-grade non-Hodgkin B-cell lymphoma.
Conclusions
It is important to put in consideration that PSL although a rare, but must be considered as a differential diagnosis, in a patient with splenomegaly and abdominal pain in absence of specific clinical findings.