Consequences and factors associated with OSA: a brief review

IF 1 4区生物学 Q3 BIOLOGY

Biological Rhythm Research Pub Date : 2022-03-28 DOI:10.1080/09291016.2022.2054558

Noorshama Parveen, A. Parganiha

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引用次数: 1

Abstract

ABSTRACT Obstructive sleep apnea (OSA) is a sleep-related breathing disorder. It occurs due to obstruction on the upper airway of respiration. This disorder can be either complete (apnea) or partial (hypopnea). Interruption in breathing results in the production of a snoring sound, which is one of the prominent symptoms of OSA. Excessive daytime sleepiness (EDS), hypertension, diabetes, etc. are some of the commonly occurring co-morbidities of OSA. OSA is common in the population of middle-aged and elderly people, but pediatric OSA is also eminent. The occurrence of the disease is higher in males. The increasing age, male gender, higher BMI, and comorbidities, such as metabolic syndrome, and obesity are considered as risk factors and make individuals more prone to OSA. The quality of life (Qol) of the individuals also gets affected by the OSA. It also alters the circadian rhythm of various autonomic and biochemical activities of people with OSA. Although polysomnography is considered the gold standard for the diagnosis of OSA, it is very costly and time-consuming. There are many portable monitoring devices and screening questionnaires for the diagnosis of OSA. Screening of OSA before polysomnography or portable monitoring is cost-effective, quick, and productive. In this review, we have highlighted scientific studies related to various factors associated with OSA in human subjects.

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OSA的后果和相关因素：综述

摘要阻塞性睡眠呼吸暂停（OSA）是一种与睡眠相关的呼吸障碍。它是由于呼吸上呼吸道阻塞引起的。这种疾病可以是完全性的（呼吸暂停），也可以是部分性的（低通气）。呼吸中断会产生打鼾声，这是OSA的突出症状之一。日间嗜睡（EDS）、高血压、糖尿病等是OSA常见的合并症。OSA在中老年人群中很常见，但儿科OSA也很突出。这种疾病在男性中发生率较高。年龄的增加、男性、较高的BMI以及代谢综合征和肥胖等合并症被认为是危险因素，使个体更容易患OSA。OSA也会影响患者的生活质量。它还改变OSA患者各种自主神经和生物化学活动的昼夜节律。尽管多导睡眠图被认为是诊断OSA的金标准，但它非常昂贵和耗时。有许多便携式监测设备和筛查问卷可用于OSA的诊断。在多导睡眠图或便携式监测之前对OSA进行筛查具有成本效益、快速和有效性。在这篇综述中，我们强调了与人类受试者OSA相关的各种因素相关的科学研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biological Rhythm Research 生物-生理学

CiteScore

3.00

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： The principal aim of Biological Rhythm Research is to cover any aspect of research into the broad topic of biological rhythms. The area covered can range from studies at the genetic or molecular level to those of behavioural or clinical topics. It can also include ultradian, circadian, infradian or annual rhythms. In this way, the Editorial Board tries to stimulate interdisciplinary rhythm research. Such an aim reflects not only the similarity of the methods used in different fields of chronobiology, but also the fact that many influences that exert controlling or masking effects are common. Amongst the controlling factors, attention is paid to the effects of climate change on living organisms. So, papers dealing with biometeorological aspects can also be submitted. The Journal publishes original scientific research papers, review papers, short notes on research in progress, book reviews and summaries of activities, symposia and congresses of national and international organizations dealing with rhythmic phenomena.