Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report

IF 0.9 Q4 GASTROENTEROLOGY & HEPATOLOGY
Takuji Tanaka, N. Watanabe, Tomohiro Kato, R. Aoki, T. Ogiso, A. Sugiyama, E. Tomita
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引用次数: 1

Abstract

Eosinophilic esophagitis (EoE), an atopic disease of the esophagus, has become increasingly recognized over the last 15 years. The epidemiology of EoE has now been reported from many countries around the world. While the clinical diagnosis of this disease depends on the patient’s clinical manifestations, the final diagnosis should be made based on the histopathological examination of esophageal mucosal biopsies. In the diagnosis of EoE, to facilitate the appropriate treatment of patients, it is extremely important to precisely recognize the presence of eosinophils in biopsy specimens of the esophageal mucosa. If eosinophils are present, EoE patients should be referred to an allergist for appropriate management with dietary modification, pharmacological agents (including corticosteroids), and/or mechanical dilation of the esophagus. We herein present and recommend the use of direct fast scarlet staining for the easy and precise recognition of eosinophils in biopsy specimens of the esophageal mucosa, a technique that has been routinely used in our laboratory.
直接快速Scarlet染色在嗜酸性食管炎组织病理学诊断中的应用
嗜酸性粒细胞性食管炎(EoE)是一种食道特应性疾病,在过去15年中得到了越来越多的认可。EoE的流行病学目前已在世界许多国家报道。虽然这种疾病的临床诊断取决于患者的临床表现,但最终诊断应基于食道粘膜活检的组织病理学检查。在EoE的诊断中,为了便于患者的适当治疗,准确识别食管黏膜活检标本中嗜酸性粒细胞的存在是极其重要的。如果存在嗜酸性粒细胞,应将EoE患者转诊至过敏专科医生,通过饮食调整、药物(包括皮质类固醇)和/或食道机械扩张进行适当管理。我们在此提出并建议使用直接快速猩红色染色,以便在食道粘膜活检标本中轻松准确地识别嗜酸性粒细胞,这是我们实验室常规使用的技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.50
自引率
0.00%
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审稿时长
10 weeks
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