Logistic planning for pharmaceutical supply chain using multi-objective optimization model

IF 1.2 Q4 HEALTH POLICY & SERVICES
M. Ershadi, Mohamad Sajad Ershadi
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引用次数: 5

Abstract

Purpose Appropriate logistic planning for the pharmaceutical supply chain can significantly improve many financial and performance aspects. To this aim, a multi-objective optimization model is proposed in this paper that considers different types of pharmaceuticals, different vehicles with determining capacities and multi-period logistic planning. This model can be updated based on new information about resources and newly identified requests. Design/methodology/approach The main objective function of the proposed model in this paper is minimizing the unsatisfied prioritized requests for pharmaceuticals in the network. Besides, the total transportation activities of different types of vehicles and related costs are considered as other objectives. Therefore, these objectives are optimized hierarchically in the proposed model using the Lexicographic method. This method finds the best value for the first objective function. Then, it tries to optimize the second objective function while maintaining the optimality of the first objective function. The third objective function is optimized based on the optimality of other objective functions, as well. A non-dominated sorting genetic algorithm II-multi-objective particle swarm optimization heuristic method is designed for this aim. Findings The performances of the proposed model were analyzed in different cases and its results for different problems were shown within the framework of a case study. Besides, the sensitivity analysis of results shows the logical behavior of the proposed model against various factors. Practical implications The proposed methodology can be applied to find the best logistic plan in real situations. Originality/value In this paper, the authors have tried to use a multi-objective optimization model to guide and correct the pharmaceutical supply chain to deal with the related requests. This is important because it can help managers to improve their plans.
基于多目标优化模型的医药供应链物流规划
目的对药品供应链进行适当的物流规划可以显著改善许多财务和绩效方面。为此,本文提出了一个多目标优化模型,该模型考虑了不同类型的药品、具有决定能力的不同车辆和多阶段物流规划。可以基于关于资源的新信息和新识别的请求来更新该模型。设计/方法/方法本文提出的模型的主要目标函数是最小化网络中未满足的药品优先请求。此外,不同类型车辆的总运输活动和相关成本也被视为其他目标。因此,在所提出的模型中,使用词典方法对这些目标进行了分层优化。该方法为第一个目标函数找到最佳值。然后,它试图优化第二个目标函数,同时保持第一个目标函数的最优性。第三个目标函数也是基于其他目标函数的最优性进行优化的。为此,设计了一种非支配排序遗传算法Ⅱ多目标粒子群优化启发式方法。结果分析了所提出的模型在不同情况下的性能,并在案例研究的框架内展示了其在不同问题下的结果。此外,结果的敏感性分析显示了所提出的模型对各种因素的逻辑行为。实际意义所提出的方法可用于在实际情况下寻找最佳物流计划。原创性/价值在本文中,作者试图使用多目标优化模型来指导和纠正药品供应链的相关要求。这一点很重要,因为它可以帮助管理者改进他们的计划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.10
自引率
8.30%
发文量
21
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