Research progress on mycoplasma pneumoniae infection and high-density lipoprotein metabolism

Abstract

Mycoplasma pneumoniae is a Gram-negative bacterium without cell wall, which mainly invades the respiratory tract and also can cause multi-system damage.Studies have shown that high-density lipoprotein can bind and neutralize lipopolysaccharide in the cell wall of Gram-negative bacteria and phosphoric acid in the cell wall of Gram-positive bacteria, inhibiting inflammation and protecting the body during pathogen infection.Because mycoplasma pneumoniae lacks cell walls, there were almost no studies about high density lipoprotein metabolism changes during mycoplasma pneumoniae infection.This paper will review the research progress of mycoplasma pneumoniae infection and high-density lipoprotein metabolism. Key words: Mycoplasma pneumoniae; Bacteria; Infection; Cell wall; Teichoic acids; Lipoproteins, HDL; Lipopolysaccharides; Review