Cardiovascular complications in coronavirus disease-2019 patients

IF 0.2 Q4 ANESTHESIOLOGY
Nirav Parikh, Hasmukh Patel, Deepal Prajapti, Ankit Chauhan, Mrugesh Prajapati, R. Patel, Himani Pandya, V. Arora, Deepti Dhawalikar
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Abstract

Background and Aims: Cardiovascular (CV) complications of coronavirus disease 2019 (COVID-19) are neither well-defined nor comprehensively characterized. Hence, long-term studies are required to monitor silent but progressive CV complications postrecovery in COVID-19 patients. Our aim of the study was to assess and determine the presence of CV morbidity and mortality in COVID-19 patients. Materials and Methods: A retrospective study was conducted at our institute. All COVID-19-positive patients who were admitted in the intensive care unit during April 3, 2020–May 23, 2021, were recruited for the study. A total of 1460 patients were enrolled and monitored until discharge/death. Patients were evaluated based on demographics, clinical data, and laboratory values and 42 patients among them underwent coronary angiography for an adequate understanding of CV complications. Results: The total reported deaths among the study sample were 453 (31%). Common preexisting clinical conditions among them were hypertension 520 (35.6%), diabetes 211 (14.45%), CV disease 88 (6.02%), and hypothyroidism 61 (4.17%). A total of 149 patients displayed elevated creatine phosphokinase-MB (CPK-MB) levels, while 141 patients displayed elevated hs-TnI levels. The absolute rise of cardiac troponin (hs-TnI) and CPK-MB displayed a technically positive correlation, but a weaker relationship (r: 0.2113, P < 0.01 for correlation). Twenty-two out of 42 patients showed the presence of single/multivessel disease and 31 patients displayed mild-to-severe left ventricular dysfunction. Conclusions: The results of the current study provide evidence for the risk and burden of CV complications among COVID-19 patients. Hence, attention to long-term CV health and disease among COVID-19 survivors is necessary.
2019年冠状病毒病患者的心血管并发症
背景和目的:2019冠状病毒病(COVID-19)的心血管(CV)并发症既没有明确的定义,也没有全面的特征。因此,需要长期研究来监测COVID-19患者康复后无症状但进展的CV并发症。我们的研究目的是评估和确定COVID-19患者中CV发病率和死亡率的存在。材料与方法:在我院进行回顾性研究。研究招募了2020年4月3日至2021年5月23日期间入住重症监护病房的所有covid -19阳性患者。共有1460名患者入组并进行监测,直至出院/死亡。根据人口统计学、临床数据和实验室值对患者进行评估,其中42例患者接受了冠状动脉造影,以充分了解心血管并发症。结果:研究样本中报告的死亡总数为453例(31%)。其中高血压520例(35.6%)、糖尿病211例(14.45%)、心血管疾病88例(6.02%)、甲状腺功能减退61例(4.17%)。共有149例患者显示肌酸磷酸激酶- mb (CPK-MB)水平升高,141例患者显示hs-TnI水平升高。心肌肌钙蛋白(hs-TnI)绝对升高与CPK-MB呈技术正相关,但相关性较弱(r: 0.2113, P < 0.01)。42例患者中有22例出现单/多血管疾病,31例出现轻至重度左心室功能障碍。结论:本研究结果为COVID-19患者CV并发症的风险和负担提供了证据。因此,有必要关注COVID-19幸存者的长期CV健康和疾病。
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来源期刊
Indian Anaesthetists Forum
Indian Anaesthetists Forum ANESTHESIOLOGY-
自引率
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发文量
17
审稿时长
6 weeks
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