Primary peritoneal carcinosarcoma arising from the secondary Müllerian system: case report and literature review

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY
Rohini V. Kulkarni, R. Bhat, Vibhawari Dhakharia, Jagannath Dixit, A. Gangoli, K. Sharma
{"title":"Primary peritoneal carcinosarcoma arising from the secondary Müllerian system: case report and literature review","authors":"Rohini V. Kulkarni, R. Bhat, Vibhawari Dhakharia, Jagannath Dixit, A. Gangoli, K. Sharma","doi":"10.1080/20742835.2018.1454144","DOIUrl":null,"url":null,"abstract":"Carcinosarcomas, also known as malignant mixed Müllerian tumours (MMMT), are aggressive neoplasms that are biphasic as they contain both carcinomatous and sarcomatous elements. Most commonly arising from the endometrium, extragenital carcinosarcomas are extremely rare and most cases develop from the peritoneum. The case is reported of a 70-year-old female who presented with abdominal pain and distention. On evaluation a large abdomino-pelvic mass with ascites was noted. She underwent complete cytoreductive surgery and the histopathology reported carcinosarcoma of primary peritoneal origin, of heterologous type arising de novo from the secondary Müllerian system with no synchronous or metachronous carcinomas or endometriosis. She declined adjuvant treatment and re-presented with disseminated abdominal disease and unfortunately succumbed to the disease within four months. Carcinosarcomas of the extragenital sites have been postulated to arise from pre-existing foci of endometriosis, Müllerian duct remnants, or the secondary Müllerian system, all of which are derivatives of the coelomic epithelium. They are extremely aggressive, and there is little knowledge concerning their natural history and scant data regarding their management.","PeriodicalId":41638,"journal":{"name":"Southern African Journal of Gynaecological Oncology","volume":"10 1","pages":"16 - 18"},"PeriodicalIF":0.1000,"publicationDate":"2018-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20742835.2018.1454144","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Southern African Journal of Gynaecological Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20742835.2018.1454144","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 1

Abstract

Carcinosarcomas, also known as malignant mixed Müllerian tumours (MMMT), are aggressive neoplasms that are biphasic as they contain both carcinomatous and sarcomatous elements. Most commonly arising from the endometrium, extragenital carcinosarcomas are extremely rare and most cases develop from the peritoneum. The case is reported of a 70-year-old female who presented with abdominal pain and distention. On evaluation a large abdomino-pelvic mass with ascites was noted. She underwent complete cytoreductive surgery and the histopathology reported carcinosarcoma of primary peritoneal origin, of heterologous type arising de novo from the secondary Müllerian system with no synchronous or metachronous carcinomas or endometriosis. She declined adjuvant treatment and re-presented with disseminated abdominal disease and unfortunately succumbed to the disease within four months. Carcinosarcomas of the extragenital sites have been postulated to arise from pre-existing foci of endometriosis, Müllerian duct remnants, or the secondary Müllerian system, all of which are derivatives of the coelomic epithelium. They are extremely aggressive, and there is little knowledge concerning their natural history and scant data regarding their management.
继发于勒氏系统的原发性腹膜癌肉瘤:病例报告及文献复习
癌肉瘤,也被称为恶性混合性勒氏瘤(MMMT),是一种侵袭性肿瘤,是双相的,因为它们同时含有癌性和肉瘤性成分。子宫外癌肉瘤通常起源于子宫内膜,极为罕见,大多数病例起源于腹膜。病例报告为一名70岁女性,表现为腹痛和腹胀。在评估中发现一个大的腹部-骨盆肿块伴腹水。她接受了完全的细胞减少手术,组织病理学报告原发性起源于腹膜的异源型癌肉瘤,起源于继发性勒氏系统,无同步或异时性癌或子宫内膜异位症。她拒绝辅助治疗并再次出现弥散性腹部疾病,不幸的是在四个月内死于疾病。外生殖器部位的癌肉瘤被认为是由先前存在的子宫内膜异位症灶、粗勒氏管残余或继发性粗勒氏管系统引起的,所有这些都是体腔上皮的衍生物。它们极具攻击性,人们对它们的自然历史知之甚少,对它们的管理也缺乏数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
24 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信