Bullous Sweet’s Syndrome in a Patient with Metastatic Colorectal Cancer

Abstract

253 Sweet’s syndrome was described in 1964 as an “acute febrile neutrophilic dermatosis”. It presents with fever, neutrophilia and tender erythematous lesions on the skin including papules, nodules and plaques. The classic histopathological finding of this disease is a diffuse infiltration of mature neutrophils in the upper dermis. The presentation of Sweet’s syndrome can be malignancy-associated, drug-induced, and idiopathic or classical1. The skin lesions associated with malignancy are frequently atypical, vesicular, bullous or even ulcerative, in addition to the typical plaques and nodules2.