A Prospective Observational Study on Prevalence of Anemia, Associated Risk Factors and Outcome

Phocas Havugimana, R. Ndahimana, F. Babane, E. Umutesi, P. Ntihinyurwa, Diane Mushimiyimana, F. Masaisa, E. Ntabanganyimana
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Abstract

Background: Admitted patients with anemia are at increased morbidity and mortality risk, as well as length of hospital stay. It affects more than 2 billion people worldwide and is causing significant morbidity and mortality. Its etiology is variable, with many predisposing factors including nutritional deficiencies, infections, malignancies, chronic inflammations, and other chronic diseases like autoimmune diseases, chronic liver disease, and chronic kidney disease. Methods: We performed a non-randomized, prospective observational study of 143 patients admitted to internal medicine between March and April 2021 and assessed their hemoglobin level in order to determine the prevalence of anemia. The demographic and clinical data were collected using a specially designed questionnaire. All patients found to have anemia were followed for outcome assessment (either discharge or death). Results: The prevalence of anemia was high (52.4%) among the 143 admitted patients in internal medicine at CHUK. Patients with HIV, cancer, and chronic kidney disease had a 5.84-, 4.11-, and 3.79-times higher risk of having anemia, respectively. In 75 patients who had anemia, 10 patients died; among them, 5 patients had severe anemia; 25 patients were 60 years old and above; 60 patients had normocytic anemia, and they had an average length of hospital stay of 20.6 days; for patients with severe anemia, the length of hospital stay was 28 days. Conclusion: This study demonstrated a high prevalence of anemia, which is associated with a high mortality rate among admitted patients in CHUK. Priority should be given to preventive medicine, optimal management of chronic disease, and geriatric medicine. Doi: 10.28991/SciMedJ-2022-04-02-05 Full Text: PDF
贫血患病率、相关危险因素及预后的前瞻性观察研究
背景:入院的贫血患者发病率和死亡率增加,住院时间也增加。它影响到全世界20多亿人,并造成严重的发病率和死亡率。它的病因是可变的,有许多诱发因素,包括营养缺乏、感染、恶性肿瘤、慢性炎症和其他慢性疾病,如自身免疫性疾病、慢性肝病和慢性肾病。方法:我们对2021年3月至4月住院的143例内科患者进行了一项非随机、前瞻性观察研究,评估了他们的血红蛋白水平,以确定贫血的患病率。采用特别设计的问卷收集人口统计学和临床数据。对所有发现贫血的患者进行随访以评估结果(出院或死亡)。结果:我院143例住院内科患者贫血发生率较高(52.4%)。患有艾滋病、癌症和慢性肾脏疾病的患者患贫血的风险分别高出5.84倍、4.11倍和3.79倍。在75名患有贫血的患者中,10名患者死亡;其中重度贫血5例;60岁及以上25例;正常细胞性贫血60例,平均住院时间20.6天;重度贫血患者住院时间为28天。结论:本研究表明,在CHUK住院患者中,贫血的高患病率与高死亡率相关。重点应放在预防医学、慢性病优化管理和老年医学上。Doi: 10.28991/SciMedJ-2022-04-02-05全文:PDF
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