Shuanghuang burn ointment in vitro antibacterial activity of common fungi infectious

Haifeng Sun, Yang Wang, R. Zhai
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引用次数: 0

Abstract

Objective To evaluate the antibacterial activity of fungal infection about Shuanghuang burn ointment in vitro. Methods The clinical isolates of candida albicans, candida tropicalis, candida albicans, candida albicans, aspergillus fumigatus, aspergillus niger, aspergillus flavus and rhizopus were produced with agar plates containing bacteria.Application of modified agar diffusion method with Shuanghuang burn ointment and clotrimazole and ketoconazole were cultured.The growth status of the strain was observed and the diameter of bacteriostatic circle was determined. Results Shuanghuang burn ointment form obvious bacteriostatic ring in the culture medium of Rhizopus.Compared with clotrimazole and ketoconazole, there was significant difference(P<0.05). In the experiments of aspergillus and candida culturesm, Shuanghuang burn ointment could not form obvious bacteriostatic ring. Conclusion Shuanghuang burn ointment has certain inhibitory effect on rhizopus in vitro.There is no obvious effect on candida and aspergillus. Key words: Fungi; Burns; Traditional Chinese medicine; Shuanghuang burn ointment
双黄烧伤膏对常见感染性真菌有体外抗菌活性
目的评价双黄烧伤膏对真菌感染的体外抗菌活性。方法用含菌琼脂平板分离白色念珠菌、热带念珠菌、白色念珠菌、白色白色念珠菌、烟曲霉、黑曲霉、黄曲霉和根霉。应用改良琼脂扩散法,以双黄烧伤膏、克霉唑和酮康唑为原料进行培养。观察菌株的生长状况,测定抑菌圈的直径。结果双黄烧伤膏在根霉培养基中形成明显的抑菌环,与克霉唑、酮康唑相比有显著性差异(P<0.05),在曲霉菌和念珠菌培养实验中,双黄烧伤软膏不能形成明显的抗菌环。结论双黄烧伤膏对体外培养的根霉有一定的抑制作用。对念珠菌和曲霉菌无明显影响。关键词:真菌;烧伤;中医药;双黄烧伤膏
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