Evaluation of the Functions and Radiographic Severity of Osteonecrosis of the Head of Femur in South-west Nigeria

L. Thanni, S. Gbadegesin
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Abstract

Background: Osteonecrosis of the femoral head is likely to be a complex of diseases rather than a single entity. In sub-Saharan Africa, epidemiological studies on the subject are uncommon. Objectives: To determine hip function, radiographic severity and other characteristics of patients with osteonecrosis of the femoral head (ONFH) at presentation in a sub-Saharan Africa population Methods: A combined prospective clinical survey and retrospective chart review of patients was done. Results: Fifty hips in 44 patients were studied (29 retrospectively and 15 prospectively). The prevalence of ONFH was 1.6%. The mean age was 24.8±13.2 years. The lesion was unilateral in 86.4% and bilateral in 13.6% of the hips. Sickle Cell Disease (SCD) occurred in 43.2%, sickle cell trait in 13.6%, and 20.5% of cases were idiopathic. Overall, 12% of affected hips were presented early, and all the hips were painful at presentation. Of the 18 hips studied prospectively, 72.2% had necrosis >30% and >30% subchondral collapse in 61.1%. The mean combined necrotic angle was moderate size, 197o±29.7o and 177.2o±69.4o for the right and left hips, respectively (p = 0.8). The mean WOMAC scores were 37.2 ±17.4 for function, 10.2±4.3 for pain and 4.2±2.7 for stiffness. Conclusion: Patients with osteonecrosis of the femoral head tended to be young adults and those with SCD. The majority present with large-sized osteonecrosis and subchondral collapse but moderate hip pain and stiffness.
尼日利亚西南部股骨头骨坏死的功能和影像学严重程度评价
背景:股骨头坏死可能是一种复杂的疾病,而不是一个单一的实体。在撒哈拉以南非洲,有关这一主题的流行病学研究并不常见。目的:确定撒哈拉以南非洲人群中股骨头坏死(ONFH)患者的髋关节功能、放射学严重程度和其他特征。方法:对患者进行前瞻性临床调查和回顾性图表回顾。结果:对44例患者的50个髋关节进行了研究(回顾性研究29例,前瞻性研究15例)。ONFH患病率为1.6%,平均年龄24.8±13.2岁。单侧病变占86.4%,双侧病变占13.6%。镰状细胞病(SCD)发生率为43.2%,镰状细胞特征发生率为13.6%,20.5%的病例为特发性。总体而言,12%的受影响髋关节早期出现,所有髋关节在出现时都很疼痛。在前瞻性研究的18个髋关节中,72.2%的髋关节坏死>30%,61.1%的髋关节软骨下塌陷>30%。平均合并坏死角度中等,右髋和左髋分别为197o±29.7o和177.2o±69.4o(p=0.8)。平均WOMAC评分为37.2±17.4(功能)、10.2±4.3(疼痛)和4.2±2.7(僵硬)。结论:股骨头坏死患者多为年轻人和SCD患者。大多数表现为大面积骨坏死和软骨下塌陷,但中度髋关节疼痛和僵硬。
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