Association of IgG and IgM Levels of CMV Infection with Abortion among Women who Smoke

Q4 Medicine

Journal of Communicable Diseases Pub Date : 2022-12-31 DOI:10.24321/0019.5138.202297

Hafidh l AI Adi

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引用次数: 0

Abstract

Introduction: Human Cytomegalovirus (CMV) infection has become common worldwide. The current study was suggested to evaluate the impact of smoking on abortion in Human Cytomegalovirus (CMV) infected women. Method: The study was conducted on 66 women IgG and IgM were used to detect CMV infection in women who had undergone abortion. Results: The current results showed significant differences in the number of births and marriage duration (p=0.009, p=0.010) and non-significant difference in age (p=0.750) in both groups. There was a high percentage of smokers (21.21%) in women with abortion as compared to the healthy group. There were significant elevations of IgG (2.32 ± 0.53) and IgM (0.51 ± 0.312) levels in women who had undergone abortion (p = 0.000) as compared to healthy women. A significant inverse association between IgG level and number of abortions (p=0.019), and a non-significant weak correlation between IgM and number of abortions (p=0.969) was noted. The impact of smoking on the number of abortions and birth showed non-significant differences (p=0.871, p=0.955) respectively between smoker and non-smoker groups. Healthy women didn’t have any abortion and showed non-significant differences in the number of births (p=0.430) in comparison with abortion group. The effect of smoking on the levels of IgG and IgM of study groups shows non-significant changes. Conclusion: The current study concluded that smoking does not contribute to abortion in any direct effect, but it may lead to CMV infection by weakening the immune response.

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吸烟妇女巨细胞病毒感染IgG和IgM水平与流产的关系

引言：人类巨细胞病毒（CMV）感染已在世界范围内变得普遍。本研究旨在评估吸烟对人类巨细胞病毒（CMV）感染妇女流产的影响。方法：对66例流产妇女进行血清IgG和IgM检测。结果：目前的结果显示，两组的出生人数和结婚时间有显著差异（p=0.009，p=0.010），年龄无显著差异（p=0.750）。与健康组相比，堕胎妇女中吸烟者的比例很高（21.21%）。与健康女性相比，流产女性的IgG（2.32±0.53）和IgM（0.51±0.312）水平显著升高（p=0.000）。IgG水平与流产次数呈显著负相关（p=0.019），IgM与流产次数无显著弱相关性（p=0.069）。吸烟对堕胎和分娩次数的影响在吸烟者和非吸烟者组之间分别显示出无显著差异（p=0.871，p=0.955）。与堕胎组相比，健康女性没有进行任何堕胎，分娩次数无显著差异（p=0.430）。吸烟对研究组IgG和IgM水平的影响没有显著变化。结论：目前的研究得出结论，吸烟对流产没有任何直接影响，但它可能通过削弱免疫反应而导致CMV感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Communicable Diseases Medicine-Infectious Diseases

CiteScore

0.40

自引率

0.00%

发文量

期刊介绍： Journal of Communicable Diseases (E-ISSN: 0019-5138 & P-ISSN: 2394-7047) is published by ADR Publications and is the official publication of Indian Society of Malaria and Other Communicable Diseases. Journal of Communicable Diseases covers scientific researches in the field of communicable diseases. Accept articles with scientific excellence in the form of (1) Original articles in basic and field research (2) Critical reviews, (3) surveys, (4) Case studies, (5) opinions/Correspondence/letters to editor, etc. The first issue of the publication entitled “Bulletin of the National Society of India for Malaria and Other Mosquito-Borne Diseases” the precursor of “Journal of Communicable Disease” (J Commun Dis) was brought out in 1953. The objects and purposes of J Commun Dis are: • to advance knowledge regarding the cause, prevalence, epidemiology, treatment, prevention and control of malaria and other-mosquito-borne diseases and other communicable diseases, • to stimulate scientific and practical interest among individuals and organizations in the prompt and effective application of treatment and control methods, • to integrate scientific and field activities and co-ordinate various scientific investigations, • to disseminate such knowledge both to scientists and to the general public.