Curcumin- Breast Cancer Therapeutic Agent to Replace Allopathic Treatments with Extensive Side Effects

Abstract

one in eight women have been affected due to breast cancer. This disease impacts over 1.5 million women each year and also causes the greatest number of cancer-related deaths among women. A research study by Siegel, Miller, and Jemal (2017) showed that approximately 231,840 new kinds of invasive breast cancer were determined among women. Furthermore, 60,290 cases were added in its natural breast cancer. From 2012 to 2015, over 40,290 cancer patients, especially women passed away due to the breast cancer. Breast cancer is one of leading causes (world’s second position) of death among both men and women. There are two types of breast cancer: non-invasive breast cancer and invasive breast cancer (Susan, 2016b). Early breast cancer that is confined to a very specific area of the breast and has not spread to surrounding tissues in the breast or armpit is known as non-invasive breast cancer. Non-invasive breast cancer (pre-cancerous) is an initial stage in which abnormal cells have not spread into the surrounding tissues. Early breast cancers that have spread beyond a very specific area of the breast to the surrounding area and/or armpit tissue are known as early invasive breast cancer. Invasive breast cancer usually first spreads to the lymph nodes from the original site, and then into the surrounding breast tissue. Mucinous (colloid) carcinoma, papillary carcinoma, and tubular carcinoma are types of invasive breast cancer. A new bump or mass in the breast is a common indicator of breast cancer. Symptoms include skin irritation or dimpling, swellINTRODUCTION Cancer is a collection of more than 100 diseases which is uncontrollable and incurable in nature. It may occur at any time and any at age and in any part of the body and is a major health burden in both developed and developing countries (Bhagat & Chaturvedi, 2016). As of 2009, the number of cancer patients has increased continuously (Ali, Wani, & Saleem, 2011). Around 8.8 million cancer patients died in 2015 and 1 in 6 patients died due to cancer. Cancer is a family of diseases in which cells in the tissues of the body grow and divide without normal control (Yasmin, Sharif, & Mohsin, 2013). This uncontrolled division of cells aggregates the cells and forms a mass or lump called a tumor. These tumors may be cancerous or non-cancerous, which is also known as malignant and benign respectively. Malignant tumors can grow and spread (metastasize) to distant areas of the body. According to Susan (2016a), Curcumin Breast Cancer Therapeutic Agent to Replace Allopathic Treatments with Extensive Side Effects